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Serotonin Uptake Inhibitors
Research News and Information
Definition of 'Serotonin Uptake Inhibitors'Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here. |
Saturday, November 21, 2009
Depletion of selective serotonin reuptake inhibitors during sewage sludge composting.
30 Oct 2009 
Sewage and sewage sludge is known to contain pharmaceuticals, and since sewage sludge is often used as fertilizer within agriculture, the reduction of the selective serotonin reuptake inhibitors (SSRIs) Citalopram, Sertraline, Paroxetine, ... Read more...
Association between the use of serotonin receptor 2A-blocking antidepressants and joint disorders.
13 Oct 2009 OBJECTIVE: There are case reports about antidepressants causing arthritis and arthralgia, and the majority of these reports deal with atypical antidepressants, which are serotonin receptor 2A (5-HT(2A))-blocking substances. The aim of this study was ... Read more...
[Narcolepsy and other hypersomnias]
6 Oct 2009 BACKGROUND: Narcolepsy is currently categorized into three groups; narcolepsy with and without emotionally triggered loss of muscle tone (cataplexy), and narcolepsy secondary to other medical conditions. Many patients with hypersomnia are diagnosed ... Read more...
Latest indexed articles for 'Serotonin Uptake Inhibitors'
These are the very latest articles for this heading:
- Ziprasidone and citalopram use in pregnancy and lactation in a woman with psychotic depression.
30 Oct 2009 - Depletion of selective serotonin reuptake inhibitors during sewage sludge composting. 30 Oct 2009
- SSRIs and congenital defects. Spontaneous publishing and academic miscarriages (SPAM). 19 Oct 2009
- Women should give informed consent before starting SSRIs. 19 Oct 2009
- SSRIs and heart defects in neonates. 19 Oct 2009
- SSRIs and congenital defects. Case registers in pregnancy? 19 Oct 2009
- Association between the use of serotonin receptor 2A-blocking antidepressants and joint disorders. 13 Oct 2009
- [Narcolepsy and other hypersomnias] 6 Oct 2009
- [Benzodiazepine reduction does not imply an increased consumption of antidepressants. A survey of two medical practices] 3 Oct 2009
- Drug fails to subdue repetitive behavior in children with autism spectrum disorders. 29 Sep 2009
- Treating premenstrual dysphoric disorder. Options include drugs targeting serotonin and various types of hormone therapy. 29 Sep 2009
- Tamoxifen, antidepressants, and CYP2D6: the conundrum continues. 29 Sep 2009
- Selective serotonin reuptake inhibitor exposure in utero and pregnancy outcomes. 29 Sep 2009
- In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. 29 Sep 2009
- Parathyroid surgery and methylene blue: a review with guidelines for safe intraoperative use. 29 Sep 2009
- Antidepressant use and preterm birth. 29 Sep 2009
- Treatment of neuropathic pain: an overview of recent guidelines. 29 Sep 2009
- Pharmacotherapy for depressed pregnant women: overcoming obstacles to gathering essential data. 29 Sep 2009
- Benefits exceed risks of newer antidepressant medications in youth--maybe not. 29 Sep 2009
- Benefits exceed risks of newer antidepressant medications in youth--maybe. 29 Sep 2009
See a longer list of these articles.
Technical information about 'Serotonin Uptake Inhibitors'
Definition: Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.
Registry Number: 0
Descriptor UI: D017367
Alternative terms: Serotonin Uptake Inhibitors; Uptake Inhibitors, 5-HT; Uptake Inhibitors, 5 HT; 5-HT Uptake Inhibitors; 5 HT Uptake Inhibitors; Inhibitors, 5-Hydroxytryptamine Uptake; Inhibitors, 5 Hydroxytryptamine Uptake; Uptake Inhibitors, 5-Hydroxytryptamine; Uptake Inhibitors, 5 Hydroxytryptamine; Inhibitors, Serotonin Reuptake; Reuptake Inhibitors, Serotonin; Serotonin Reuptake Inhibitors; Inhibitors, Serotonin Uptake; Uptake Inhibitors, Serotonin; Inhibitors, 5-HT Uptake; Inhibitors, 5 HT Uptake; 5-Hydroxytryptamine Uptake Inhibitors; 5 Hydroxytryptamine Uptake Inhibitors;
Related Mesh Headings: Antidepressive Agents, Second-Generation; Adrenergic Uptake Inhibitors;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D27.505.519.625.600.850; D27.505.519.625.850.900; D27.505.696.577.600.850; D27.505.696.577.850.900;
History Note: 93
Technical Notes: GEN or unspecified; prefer specifics; do not confuse with SEROTONIN ANTAGONISTS; DF: SEROTONIN UPTAKE INHIB