Serotonin
Research News and Information

Saturday, November 21, 2009

Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.

2 Nov 2009 Receptor (type II) taste bud cells secrete ATP during taste stimulation. In turn, ATP activates adjacent presynaptic (type III) cells to release serotonin (5-hydroxytryptamine, or 5-HT) and norepinephrine (NE). The roles of these neurotransmitters ... Read more...

Equal contribution of increased intracranial pressure and subarachnoid blood to cerebral blood flow reduction and receptor upregulation after subarachnoid hemorrhage. Laboratory investigation.

30 Oct 2009 OBJECT: Cerebral ischemia remains the key cause of disability and death in the late phase after subarachnoid hemorrhage (SAH), and its pathogenesis is still poorly understood. The purpose of this study was to examine whether the change in ... Read more...

Fast synaptic subcortical control of hippocampal circuits.

14 Oct 2009 Cortical information processing is under state-dependent control of subcortical neuromodulatory systems. Although this modulatory effect is thought to be mediated mainly by slow nonsynaptic metabotropic receptors, other mechanisms, such as direct ... Read more...

Latest indexed articles for 'Serotonin'

These are the very latest articles for this heading:

• Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. 2 Nov 2009
• Deciphering the interaction of the corticotropin-releasing factor and serotonin brain systems in anxiety-related disorders. 2 Nov 2009
• Equal contribution of increased intracranial pressure and subarachnoid blood to cerebral blood flow reduction and receptor upregulation after subarachnoid hemorrhage. Laboratory investigation. 30 Oct 2009
• Fast synaptic subcortical control of hippocampal circuits. 14 Oct 2009
• MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning. 29 Sep 2009
• Comparative effects of furnished and battery cages on egg production and physiological parameters in White Leghorn hens. 29 Sep 2009
• Effects of group size and repeated social disruption on the serotonergic and dopaminergic systems in two genetic lines of White Leghorn laying hens. 29 Sep 2009
• Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. 29 Sep 2009
• Combined administration of the mixture of honokiol and magnolol and ginger oil evokes antidepressant-like synergism in rats. 24 Sep 2009
• Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. 22 Sep 2009
• Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. 21 Sep 2009
• Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord. 14 Sep 2009
• Spontaneous activity in the developing mouse midbrain driven by an external pacemaker. 13 Sep 2009
• Serotonergic modulation of basal ganglia circuits: complexity and therapeutic opportunities. 13 Sep 2009
• Serotonin targets inhibitory synapses to induce modulation of network functions. 10 Sep 2009
• The use of viral gene transfer in studies of brainstem noradrenergic and serotonergic neurons. 10 Sep 2009
• Differential regulation of the central neural cardiorespiratory system by metabotropic neurotransmitters. 10 Sep 2009
• The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice. 6 Sep 2009
• A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. 2 Sep 2009
• Mechanisms by which the serotonergic system inhibits micturition in rats. 31 Aug 2009

See a longer list of these articles.

Technical information about 'Serotonin'

Definition: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Chemical name: 1H-Indol-5-ol, 3-(2-aminoethyl)-

Registry Number: 50-67-9

Descriptor UI: D012701

Alternative terms: Serotonin; 5-Hydroxytryptamine; 5 Hydroxytryptamine; 3-(2-Aminoethyl)-1H-indol-5-ol; 5-HT; Enteramine; Hippophaine; Hydroxytryptamine;

Related Mesh Headings: Receptors, Serotonin; Serotonin Agents; Serotonin Syndrome;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: Serotonin Agents;

Tree Number: D02.092.211.215.801.852; D03.438.473.914.814; D23.469.050.650;

Online Note: use SEROTONIN to search HYDROXYTRYPTAMINE 1975-92

History Note: HYDROXYTRYPTAMINE was see SEROTONIN 1975-92

Technical Notes: /antag = SEROTONIN ANTAGONISTS but consider also SEROTONIN UPTAKE INHIBITORS