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Sleep Apnea, Obstructive
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Definition of 'Sleep Apnea, Obstructive'

A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

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Tuesday, November 24, 2009

High prevalence of abnormal nocturnal oximetry in patients with hypertrophic cardiomyopathy.

Nov 2009 OBJECTIVES: We sought to determine the prevalence of nocturnal oxygen desaturation and obstructive sleep apnea (OSA) in a population of patients with hypertrophic cardiomyopathy (HCM). BACKGROUND: The coexistence of sleep apnea and HCM, 2 common ... Read more...


Effects of alcohol and sleep restriction on simulated driving performance in untreated patients with obstructive sleep apnea.

4 Oct 2009 BACKGROUND: Because of previous sleep disturbance and sleep hypoxia, patients with obstructive sleep apnea (OSA) might be more vulnerable to the effects of alcohol and sleep restriction than healthy persons. OBJECTIVE: To compare the effects of ... Read more...


The expression of vascular endothelial growth factor in skeletal muscle of patients with sleep disorders.

29 Sep 2009 An increased capillary network has been observed in skeletal muscle of patients with restless legs syndrome (RLS) and obstructive sleep apnea syndrome (OSAS). This finding could be due to upregulation of growth factors responsible for angiogenesis. ... Read more...

 

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Technical information about 'Sleep Apnea, Obstructive'

Definition: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Descriptor UI: D020181

Alternative terms: Sleep Apnea, Obstructive; Apnea, Obstructive Sleep; Apneas, Obstructive Sleep; Obstructive Sleep Apneas; Sleep Apneas, Obstructive; Obstructive Sleep Apnea Syndrome; Syndrome, Sleep Apnea, Obstructive; Syndrome, Obstructive Sleep Apnea; Obstructive Sleep Apnea; Sleep Apnea Syndrome, Obstructive; Upper Airway Resistance Sleep Apnea Syndrome; Syndrome, Upper Airway Resistance, Sleep Apnea;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C08.618.085.852.850; C10.886.425.800.750.850;

History Note: 2000

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