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Small Ubiquitin-Related Modifier Proteins - Chemistry
Research News and Information
Definition of 'Small Ubiquitin-Related Modifier Proteins'A class of structurally related proteins of 12-20 kDa in size. They covalently modify specific proteins in a manner analogous to UBIQUITIN. Common names: Small Ubiquitin-Related Modifier Proteins; Small Ubiquitin Related Modifier Proteins; Ubiquitin-Related Modifier Protein, Small; Ubiquitin Related Modifier Protein, Small; Sentrins; Sentrin Proteins; SUMO Proteins |
Sunday, November 22, 2009
A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9.
14 Aug 2009 
Phosphorylation and small ubiquitin-like modifier (SUMO) conjugation contribute to the spatial and temporal regulation of substrates containing phosphorylation-dependent SUMO consensus motifs (PDSMs). Myocyte-enhancement factor 2 (MEF2) is a ... Read more...
A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays.
30 Jul 2009 The posttranslational modification of target substrates by the ubiquitin-like proteins, specifically the small ubiquitin-like modifier (SUMO), has emerged as an essential mechanism to regulate protein function and control intracellular trafficking. ... Read more...
SUMO association with repressor complexes, emerging routes for transcriptional control.
15 Jul 2009 Covalent attachment of the small ubiquitin-like modifier (SUMO) to proteins constitutes a posttranslational modification intensely studied during the last decade. From the many proteins that serve as SUMO substrates, multiple functions have been ... Read more...
Latest indexed articles for 'Small Ubiquitin-Related Modifier Proteins - Chemistry'
These are the very latest articles for this heading:
- A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9. 14 Aug 2009
- A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays. 30 Jul 2009
- SUMO association with repressor complexes, emerging routes for transcriptional control. 15 Jul 2009
- Carrier proteins for fusion expression of antimicrobial peptides in Escherichia coli. 4 Jul 2009
- Solution structure of SUMO from Trypanosoma brucei and its interaction with Ubc9.
29 Jun 2009 - Characterization of SENP7, a SUMO-2/3-specific isopeptidase. 24 Jun 2009
- Mechanical unfolding pathway and origin of mechanical stability of proteins of ubiquitin family: an investigation by steered molecular dynamics simulation. 30 May 2009
- Molecular mimicry of SUMO promotes DNA repair. 10 Apr 2009
- Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1. 11 Mar 2009
- Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. 25 Feb 2009
- Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites. 22 Feb 2009
- Essential role of nuclear localization for yeast Ulp2 SUMO protease function.
16 Feb 2009 - Using mass spectrometry to identify ubiquitin and ubiquitin-like protein conjugation sites. 30 Jan 2009
- Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. 14 Jan 2009
- Small ubiquitin-like modifiers in cellular malignancy and metastasis. 30 Dec 2008
- SUMO conjugation and cardiovascular development. 30 Dec 2008
- Identification of SUMO target proteins by quantitative proteomics. 30 Dec 2008
- KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors. 22 Nov 2008
- The fast-growing business of SUMO chains. 5 Nov 2008
- DeSUMOylating enzymes--SENPs. 30 Oct 2008
See a longer list of these articles.
Technical information about 'Small Ubiquitin-Related Modifier Proteins'
Definition: A class of structurally related proteins of 12-20 kDa in size. They covalently modify specific proteins in a manner analogous to UBIQUITIN.
Registry Number: 0
Descriptor UI: D025841
Alternative terms: Small Ubiquitin-Related Modifier Proteins; Small Ubiquitin Related Modifier Proteins; Ubiquitin-Related Modifier Protein, Small; Ubiquitin Related Modifier Protein, Small; Sentrins; Sentrin Proteins; SUMO Proteins;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.776.947.249;
History Note: 2002