Spasms, Infantile - Drug therapy
Research News and Information

Sunday, November 22, 2009

[A comparative study of conventional dose and low dose adrenocorticotrophic hormone therapy for West syndrome]

30 May 2009 OBJECTIVE: The efficacy and adverse effects of conventional dose and low dose adrenocorticotrophic hormone (ACTH) therapy for West syndrome (WS) were compared in order to identify a low effective dose with few adverse effects. METHODS: A prospective ... Read more...

[Temporal changes in intraocular pressure during adrenocorticotropic hormone therapy of two cases of West syndrome]

29 Apr 2009 BACKGROUND: Two cases of West syndrome demonstrated changes in intraocular pressure (IOP) associated with adrenocorticotropic hormone (ACTH) therapy. CASES: A nine-month-old (Case 1) and a six-month-old (Case 2) female infant were treated for West ... Read more...

Multicenter long-term follow-up of children with idiopathic West syndrome: ACTH versus vigabatrin.

30 Mar 2009 BACKGROUND AND PURPOSE: Long-term follow-up of children with idiopathic West syndrome (WS) treated with adrenocorticotropic hormone (ACTH) or vigabatrin. METHODS: Records of 28 normal magnetic resonance imaging (MRI) WS cases were reviewed for ... Read more...

Latest indexed articles for 'Spasms, Infantile - Drug therapy'

These are the very latest articles for this heading:

• Drug approved to treat infantile spasms. 29 Sep 2009
• Vigabatrin therapy in infantile spasms: solving one problem and inducing another? 30 Jul 2009
• Is the risk of vigabatrin-attributed visual field loss lower in infancy than in later life? 30 Jul 2009
• [A comparative study of conventional dose and low dose adrenocorticotrophic hormone therapy for West syndrome] 30 May 2009
• [Temporal changes in intraocular pressure during adrenocorticotropic hormone therapy of two cases of West syndrome] 29 Apr 2009
• Multicenter long-term follow-up of children with idiopathic West syndrome: ACTH versus vigabatrin. 30 Mar 2009
• Pyridoxine-dependent epilepsy: normal outcome in a patient with late diagnosis after prolonged status epilepticus causing cortical blindness. 15 Mar 2009
• Reduced grating acuity associated with retinal toxicity in children with infantile spasms on vigabatrin therapy. 9 Mar 2009
• Smith-Magenis syndrome with West syndrome in a 5-year-old girl: a long-term follow-up study. 2 Mar 2009
• Topiramate and adrenocorticotropic hormone (ACTH) as initial treatment for infantile spasms. 16 Feb 2009
• High-dose oral prednisolone for infantile spasms: an effective and less expensive alternative to ACTH. 2 Feb 2009
• American Epilepsy Society--62nd Annual Meeting. 5-9 December 2008, Seattle, USA. 30 Jan 2009
• Vigabatrin: 2008 update. 30 Jan 2009
• Visual fields at school-age in children treated with vigabatrin in infancy. 30 Jan 2009
• A pilot study on the changes in immunity after ACTH therapy in patients with West syndrome. 29 Dec 2008
• Magnetic resonance imaging abnormalities associated with vigabatrin in patients with epilepsy. 15 Nov 2008
• [Case of west syndrome associated with transient marked sinus dysfunction during ACTH therapy] 30 Oct 2008
• A retrospective study on aetiology based outcome of infantile spasms. 28 Oct 2008
• Justification of vigabatrin administration in West syndrome patients? Warranting a re-consideration for improvement in their quality of life. 6 Oct 2008
• Treatment of infantile spasms. 6 Oct 2008

See a longer list of these articles.

Technical information about 'Spasms, Infantile'

Definition: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)

Descriptor UI: D013036

Alternative terms: Spasms, Infantile; Infantile Spasm; Lightning Attacks; Attack, Lightning; Attacks, Lightning; Lightning Attack; West Syndrome; Syndrome, West; Infantile Spasms; Hypsarrhythmia; Hypsarrhythmias; Symptomatic Infantile Spasms; Infantile Spasm, Symptomatic; Infantile Spasms, Symptomatic; Spasm, Symptomatic Infantile; Spasms, Symptomatic Infantile; Symptomatic Infantile Spasm; Symptomatic West Syndrome; Syndrome, Symptomatic West; West Syndrome, Symptomatic; Nodding Spasm; Nodding Spasms; Spasm, Nodding; Spasms, Nodding; Salaam Attacks; Attacks, Salaam; Salaam Seizures; Seizures, Salaam; Spasmus Nutans; Cryptogenic Infantile Spasms; Cryptogenic Infantile Spasm; Infantile Spasm, Cryptogenic; Infantile Spasms, Cryptogenic; Spasm, Cryptogenic Infantile; Spasms, Cryptogenic Infantile; Cryptogenic West Syndrome; Syndrome, Cryptogenic West; West Syndrome, Cryptogenic; Jackknife Seizures; Jackknife Seizure; Seizure, Jackknife; Seizures, Jackknife;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.490.375.760;

History Note: 1977(1963)

Technical Notes: epileptic seizures only: do not confuse with SPASM + INFANT for non-epileptic seizures in inf such as in tetany or vitamin defic; check tag INFANT or INFANT, NEWBORN