Spectrometry, Mass, Electrospray Ionization - Methods
Research News and Information

Monday, November 23, 2009

Validated LC coupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoir transdermal patches using a simple and rapid procedure.

29 Sep 2009 BACKGROUND AND OBJECTIVES: Fentanyl has been used for cancer pain in transdermal formulation. The aim of the present study was to establish an analytical method for fentanyl in human plasma and in an applied transdermal reservoir patch ... Read more...

Structural characterization and identification of iridoid glycosides, saponins, phenolic acids and flavonoids in Flos Lonicerae Japonicae by a fast liquid chromatography method with diode-array detection and time-of-flight mass spectrometry.

29 Sep 2009 A fast liquid chromatography method with diode-array detection (DAD) and time-of-flight mass spectrometry (TOF-MS) has been developed for analysis of constituents in Flos Lonicerae Japonicae (FLJ), a traditional Chinese medicine derived from the ... Read more...

Characterization of novel hydrolysis products of carbapenems by electrospray ionization mass spectrometry.

29 Sep 2009 Carbapenems, including meropenem and imipenem, exhibit low stability against acid or base reagents. The fragmentation behavior of meropenem and its acid hydrolysis products was investigated by Fourier transform ion cyclotron resonance electrospray ... Read more...

Latest indexed articles for 'Spectrometry, Mass, Electrospray Ionization - Methods'

These are the very latest articles for this heading:

• Validated LC coupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoir transdermal patches using a simple and rapid procedure. 29 Sep 2009
• Structural characterization and identification of iridoid glycosides, saponins, phenolic acids and flavonoids in Flos Lonicerae Japonicae by a fast liquid chromatography method with diode-array detection and time-of-flight mass spectrometry. 29 Sep 2009
• Characterization of novel hydrolysis products of carbapenems by electrospray ionization mass spectrometry. 29 Sep 2009
• Assigning glucose or galactose as the primary glycosidic sugar in 3-O-mono-, di- and triglycosides of kaempferol using negative ion electrospray and serial mass spectrometry. 29 Sep 2009
• Mass spectrometry of intact neutral macromolecules using intense non-resonant femtosecond laser vaporization with electrospray post-ionization. 29 Sep 2009
• A rapid screening method for prenylated flavonoids with ultra-high-performance liquid chromatography/electrospray ionisation mass spectrometry in licorice root extracts. 29 Sep 2009
• Direct olive oil analysis by low-temperature plasma (LTP) ambient ionization mass spectrometry. 29 Sep 2009
• Detection of aminothiols through surface-assisted laser desorption/ionization mass spectrometry using mixed gold nanoparticles. 29 Sep 2009
• Monitoring inhibitor-induced conformational population shifts in HIV-1 protease by pulsed EPR spectroscopy. 20 Sep 2009
• Clear differences in levels of a formaldehyde-DNA adduct in leukocytes of smokers and nonsmokers. 6 Sep 2009
• pH-Dependent syntheses, structural and spectroscopic characterization, and chemical transformations of aqueous Co(II)-quinate complexes: an effort to delve into the structural speciation of the binary Co(II)-quinic acid system. 5 Sep 2009
• Spectroscopy and microscopy studies of the recognition of amino acids and aggregation of proteins by Zn(II) complex of lower rim naphthylidene conjugate of calix[4]arene. Sep 2009
• Methodology for determining disulfide linkage patterns of closely spaced cysteine residues. 30 Aug 2009
• A simple and rapid method for the determination of pennogenin diglycoside in rat plasma by HPLC-MS: application to the pharmacokinetics of the extract in Gongxuening capsules. 30 Aug 2009
• Diastereomeric differentiation of norbornene amino acid peptides by electrospray ionization tandem mass spectrometry. 30 Aug 2009
• Determination of 8-epi PGF(2alpha) concentrations as a biomarker of oxidative stress using triple-stage liquid chromatography/tandem mass spectrometry. 30 Aug 2009
• Fast analysis of isobaric grape anthocyanins by Chip-liquid chromatography/mass spectrometry. 30 Aug 2009
• Analysis of Amaryllidaceae alkaloids from Crinum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. 30 Aug 2009
• Heterobifunctional isotope-labeled amine-reactive photo-cross-linker for structural investigation of proteins by matrix-assisted laser desorption/ionization tandem time-of-flight and electrospray ionization LTQ-Orbitrap mass spectrometry. 30 Aug 2009
• The host-defence skin peptide profiles of Peron's Tree Frog Litoria peronii in winter and summer. Sequence determination by electrospray mass spectrometry and activities of the peptides. 30 Aug 2009

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Technical information about 'Spectrometry, Mass, Electrospray Ionization'

Definition: A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.

Descriptor UI: D021241

Alternative terms: Spectrometry, Mass, Electrospray Ionization; Electrospray Ionization Mass Spectrometry; ESI Mass Spectrometry; Mass Spectrometry, ESI; Spectrometry, ESI Mass;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.196.566.600;

History Note: 2001