Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Research News and Information

Saturday, November 21, 2009

Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin.

13 Nov 2009 Clear cell carcinoma (CCC) of the ovary is known to be highly resistant to platinum-based chemotherapy. The purpose of our study was to identify a candidate protein that is associated with chemoresistance of CCC and to investigate the specific ... Read more...

Importance of the conserved lysine 83 residue of Zea mays cytochrome b(561) for ascorbate-specific transmembrane electron transfer as revealed by site-directed mutagenesis studies.

8 Nov 2009 Cytochromes b(561), a novel class of transmembrane electron transport proteins residing in a large variety of eukaryotic cells, have a number of common structural features including six hydrophobic transmembrane alpha-helices and two heme ligation ... Read more...

Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling.

21 Oct 2009 We have reported previously the design of a RIAD (RI-anchoring disruptor) peptide that specifically displaces PKA (protein kinase A) type I from the AKAP (A-kinase-anchoring protein) ezrin, which is present in the immunological synapse of T-cells. ... Read more...

Latest indexed articles for 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'

These are the very latest articles for this heading:

• Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin. 13 Nov 2009
• Importance of the conserved lysine 83 residue of Zea mays cytochrome b(561) for ascorbate-specific transmembrane electron transfer as revealed by site-directed mutagenesis studies. 8 Nov 2009
• Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling. 21 Oct 2009
• Transition state analogues rescue ribosomes from saporin-L1 ribosome inactivating protein. 18 Oct 2009
• A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. 18 Oct 2009
• Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers. 12 Oct 2009
• Protein profiling of pleural effusions to identify malignant pleural mesothelioma using SELDI-TOF MS. 29 Sep 2009
• The ubiquitin-like protein monoclonal nonspecific suppressor factor beta conjugates to endophilin II and regulates phagocytosis. 29 Sep 2009
• Study of human neutrophil peptides in saliva by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 29 Sep 2009
• Study of latent fingermarks by matrix-assisted laser desorption/ionisation mass spectrometry imaging of endogenous lipids. 29 Sep 2009
• Invited commentary. 29 Sep 2009
• Serum protein profiles in myasthenia gravis. 29 Sep 2009
• Chemical dynamics of triacetylene formation and implications to the synthesis of polyynes in Titan's atmosphere. 12 Sep 2009
• Differential proteome analysis of the preeclamptic placenta using optimized protein extraction. 11 Sep 2009
• Production of a recombinant mouse monoclonal antibody in transgenic silkworm cocoons. 7 Sep 2009
• High-throughput profiling of formalin-fixed paraffin-embedded tissue using parallel electrophoresis and matrix-assisted laser desorption ionization mass spectrometry. 30 Aug 2009
• A comparative analysis of embryo and endosperm proteome from seeds of Jatropha curcas. 30 Aug 2009
• Quantification of target proteins using hydrogel antibody arrays and MALDI time-of-flight mass spectrometry (A2M2S). 30 Aug 2009
• Comparative proteomic analysis of Campylobacter jejuni cultured at 37C and 42C. 30 Aug 2009
• Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'

Definition: A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.

Descriptor UI: D019032

Alternative terms: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization; Mass Spectrometry, Matrix Assisted Laser Desorption Ionization; Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry; Matrix Assisted Laser Desorption Ionization Mass Spectrometry; MALDI; Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization; MS-MALD; MALD-MS; MALDI-MS; MALDI MS; Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted; Laser Desorption Ionization Mass Spectrometry, Matrix Assisted; Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization; Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization; Surface Enhanced Laser Desorption Ionization Mass Spectrometry; SELDI-TOF-MS;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.196.566.755;

History Note: 96