Spinal Cord Injuries - Drug therapy
Research News and Information

Sunday, November 22, 2009

[Effects of high dose methylprednisolone on cell apoptosis and Bcl-2 expression after acute spinal cord injuries in rats]

30 Aug 2009 OBJECTIVE: To investigate the effect of high dose methylprednisolone (MP) on cell apoptosis and Bcl-2 expression after acute spinal cord injury (ASCI). METHODS: The 48 female rats were randomly divided into two groups:control group and experimental ... Read more...

Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury.

18 Aug 2009 In the present study, we examined whether activation of p-38alpha MAPK modulates mechanical allodynia and neuronal hyperexcitability, and if propentofylline (PPF, a glial modulator) modulates specifically localized activated p-38alpha MAPK ... Read more...

The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions.

10 Aug 2009 Neurogenic pulmonary edema (NPE) is an acute life-threatening complication following an injury of the spinal cord or brain, which is associated with sympathetic hyperactivity. The role of nitric oxide (NO) in NPE development in rats subjected to ... Read more...

Latest indexed articles for 'Spinal Cord Injuries - Drug therapy'

These are the very latest articles for this heading:

• [Effects of high dose methylprednisolone on cell apoptosis and Bcl-2 expression after acute spinal cord injuries in rats] 30 Aug 2009
• Be careful what you train for. 30 Aug 2009
• Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury. 18 Aug 2009
• The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions. 10 Aug 2009
• Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation. 7 Aug 2009
• Steroids for acute spinal cord injury: revealing silent pathology. 6 Aug 2009
• Methylprednisolone fails to improve functional and histological outcome following spinal cord injury in rats. 5 Aug 2009
• Shengmai-san-mediated enhancement of regenerative responses of spinal cord axons after injury in rats. 30 Jul 2009
• Beneficial effects of ethyl pyruvate in a mouse model of spinal cord injury. 30 Jul 2009
• Orthostatic responses to nitric oxide synthase inhibition in persons with tetraplegia. 30 Jul 2009
• Insulin with chondroitinase ABC treats the rat model of acute spinal cord injury. 29 Jun 2009
• Methylprednisolone after traumatic spinal cord injury: yes or no? 29 Jun 2009
• Brain protection by methylprednisolone in rats with spinal cord injury. 29 Jun 2009
• Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. 29 Jun 2009
• Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury. 29 Jun 2009
• Neuromodulation in patients deployed to war zones. 29 Jun 2009
• Hypertonic saline attenuates cord swelling and edema in experimental spinal cord injury: a study utilizing magnetic resonance imaging. 29 Jun 2009
• Antiedema effects of hypertonic saline after spinal cord injury. 29 Jun 2009
• Olfactory bulb implantation and methylprednisolone administration in the treatment of spinal cord injury in rats. 24 Jun 2009
• Improved functional recovery with oxandrolone after spinal cord injury in rats. 15 Jun 2009

See a longer list of these articles.

Technical information about 'Spinal Cord Injuries'

Definition: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Descriptor UI: D013119

Alternative terms: Spinal Cord Injuries; Myelopathy, Traumatic; Myelopathies, Traumatic; Traumatic Myelopathies; Traumatic Myelopathy; Spinal Cord Trauma; Cord Trauma, Spinal; Cord Traumas, Spinal; Spinal Cord Traumas; Trauma, Spinal Cord; Traumas, Spinal Cord; Injuries, Spinal Cord; Cord Injuries, Spinal; Cord Injury, Spinal; Injury, Spinal Cord; Spinal Cord Injury; Spinal Cord Transection; Cord Transection, Spinal; Cord Transections, Spinal; Spinal Cord Transections; Transection, Spinal Cord; Transections, Spinal Cord; Spinal Cord Laceration; Cord Laceration, Spinal; Cord Lacerations, Spinal; Laceration, Spinal Cord; Lacerations, Spinal Cord; Spinal Cord Lacerations; Post-Traumatic Myelopathy; Myelopathies, Post-Traumatic; Myelopathy, Post-Traumatic; Post Traumatic Myelopathy; Post-Traumatic Myelopathies; Spinal Cord Contusion; Contusion, Spinal Cord; Contusions, Spinal Cord; Cord Contusion, Spinal; Cord Contusions, Spinal; Spinal Cord Contusions;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.854.770; C10.900.850; C21.866.819;

Technical Notes: coord IM with specific vertebra (NIM) to locate site on spinal cord