Spleen - Drug effects
Research News and Information

Sunday, November 22, 2009

Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions.

29 Sep 2009 Although originally described in tumor-bearing hosts, myeloid-derived suppressor cells (MDSC) have been detected under numerous pathological situations that cause enhanced demand of myeloid cells. Thus, MDSC might be part of a conserved response to ... Read more...

Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins modulates Treg and ameliorates inflammatory colitis.

29 Sep 2009 Pathogenic lymphocytes in the enteric wall of inflammatory bowel disease patients display various abnormalities, including reduced sensitivity to apoptosis. We evaluated a therapeutic approach to elimination of cytotoxic cells, using two IL-2 fusion ... Read more...

Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development.

29 Sep 2009 Myeloid-derived suppressor cells (MDSC) and DC are major controllers of immune responses against tumors or infections. However, it remains unclear how DC development and MDSC suppressor activity both generated from myeloid precursor cells are ... Read more...

Latest indexed articles for 'Spleen - Drug effects'

These are the very latest articles for this heading:

• Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions. 29 Sep 2009
• Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins modulates Treg and ameliorates inflammatory colitis. 29 Sep 2009
• Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development. 29 Sep 2009
• Pillars article: antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319. 29 Sep 2009
• Deoxyribonuclease I is essential for DNA fragmentation induced by gamma radiation in mice. 29 Sep 2009
• Role of TL1A in the pathogenesis of rheumatoid arthritis. 26 Sep 2009
• Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. 23 Sep 2009
• Effects of Agaricus blazei Murill extract on immune responses in normal BALB/c mice. 30 Aug 2009
• Gandoderma lucidum extract promotes immune responses in normal BALB/c mice In vivo. 30 Aug 2009
• Selection for increased nitric oxide production does not increase resistance to Marek's disease in a primary broiler breeder line. 30 Aug 2009
• Enhancing the action of rituximab in chronic lymphocytic leukemia by adding fresh frozen plasma: complement/rituximab interactions & clinical results in refractory CLL. 30 Aug 2009
• A fusion protein composed of IL-2 and caspase-3 ameliorates the outcome of experimental inflammatory colitis. 30 Aug 2009
• Postchemotherapy histiocyte-rich pseudotumor involving the spleen. 30 Aug 2009
• Immunomodulatory activity of aqueous extract of Achillea wilhelmsii C. Koch in mice. 30 Jul 2009
• The effects of telocinobufagin isolated from Chan Su on the activation and cytokine secretion of immunocytes in vitro. 30 Jul 2009
• High and low vitamin A therapies induce distinct FoxP3+ T-cell subsets and effectively control intestinal inflammation. 22 Jul 2009
• A. cantoniensis inhibits the proliferation of murine leukemia WEHI-3 cells in vivo and promotes immunoresponses in vivo. 29 Jun 2009
• Immunostimulatory activities of a low molecular weight antitumoral polysaccharide isolated from Agaricus blazei Murill (LMPAB) in Sarcoma 180 ascitic tumor-bearing mice. 29 Jun 2009
• Triptolide promotes generation of FoxP3+ T regulatory cells in rats. 24 Jun 2009
• Anti-allergic effects of white rose petal extract and anti-atopic properties of its hexane fraction. 24 Jun 2009

See a longer list of these articles.

Technical information about 'Spleen'

Descriptor UI: D013154

Alternative terms: Spleen; Spleens;

Related Mesh Headings: Splenectomy;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A10.549.700; A15.382.520.604.700;

Technical Notes: /inj: consider also SPLENIC RUPTURE but traumatic spleen perforation is indexed under SPLEEN /inj; accessory spleen: index under SPLEEN /abnorm