Startle Reaction - Drug effects
Research News and Information

Monday, November 23, 2009

Evidence for a putative biomarker for substance dependence.

30 Aug 2009 Electrodermal response modulation (ERM) reflects the reduction in skin conductance response to an aversive stimulus that is temporally predictable relative to when it is unpredictable. Poor ERM is associated with substance dependence (SD). It was ... Read more...

Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm.

30 Aug 2009 BACKGROUND: The volatile anesthetics desflurane, isoflurane, and sevoflurane have been found to produce neuroprotection in various paradigms. The authors used these agents in a delayed preconditioning model to test the hypothesis that they could ... Read more...

Downregulation of oligodendrocyte transcripts is associated with impaired prefrontal cortex function in rats.

29 Jun 2009 Abnormalities of brain white matter and oligodendroglia are among the most consistent findings in schizophrenia (Sz) research. Various gene expression microarray studies of post-mortem Sz brains showed a downregulation of myelin transcripts, while ... Read more...

Latest indexed articles for 'Startle Reaction - Drug effects'

These are the very latest articles for this heading:

• Evidence for a putative biomarker for substance dependence. 30 Aug 2009
• Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm. 30 Aug 2009
• Downregulation of oligodendrocyte transcripts is associated with impaired prefrontal cortex function in rats. 29 Jun 2009
• The developmental effects of a municipal wastewater effluent on the northern leopard frog, Rana pipiens. 24 Jun 2009
• A cholinergic-dependent role for the entorhinal cortex in trace fear conditioning. 22 Jun 2009
• Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia. 8 Jun 2009
• Interaction between the effects of corticotropin-releasing factor and prepulse parameters on prepulse inhibition in two inbred rat strains and the F1 generation of a cross between them. 6 Jun 2009
• Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition. 4 Jun 2009
• Individual differences in responses to nicotine: tracking changes from adolescence to adulthood. 30 May 2009
• TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia. 27 May 2009
• Using prepulse inhibition to detect functional D3 receptor antagonism: effects of WC10 and WC44. 4 May 2009
• Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine. 3 May 2009
• Deficits in adult prefrontal cortex neurons and behavior following early post-natal NMDA antagonist treatment. May 2009
• Augmentation of fear extinction by infusion of glycine transporter blockers into the amygdala. 29 Apr 2009
• Alcohol selectively reduces anxiety but not fear: startle response during unpredictable versus predictable threat. 29 Apr 2009
• Behavioural and toxic interaction profile of ketamine in combination with caffeine. 29 Apr 2009
• Effects of neonatal and peripubertal ethanol treatment on various aspects of adult rat behavior and brain anatomy. 29 Apr 2009
• Mood stabilizers increase prepulse inhibition in DBA/2NCrl mice. 27 Apr 2009
• Effects of cocaine self-administration history under limited and extended access conditions on in vivo striatal dopamine neurochemistry and acoustic startle in rhesus monkeys. 12 Apr 2009
• Lipopolysaccharide reduces tactile startle response magnitude but not prepulse inhibition in rats: a dose-response examination. 8 Apr 2009

See a longer list of these articles.

Technical information about 'Startle Reaction'

Definition: A complex involuntary response to an unexpected strong stimulus usually auditory in nature.

Descriptor UI: D013216

Alternative terms: Startle Reaction; Reaction, Startle; Reactions, Startle; Startle Reactions;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: E01.370.376.550.650.800; E01.370.600.550.650.800; F02.830.702.807; G11.561.600.765.869;

History Note: 69(65)

Technical Notes: human & animal