Stevens-Johnson Syndrome - Chemically induced
Research News and Information

Sunday, November 22, 2009

Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population.

30 Aug 2009 OBJECTIVES: Allopurinol, a uric acid lowering drug commonly used for hyperuricemia and gouty arthritis, has been reported as a common cause of severe cutaneous adverse drug reactions (SCAR) including Stevens-Johnson syndrome (SJS) and toxic ... Read more...

High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients.

30 Aug 2009 BACKGROUND: Severe cutaneous adverse reactions (SCARs) are associated with over 200 medicines including lamotrigine, an antiepileptic drug. Previous studies have suggested the involvement of immune mechanisms in the development of drug-induced ... Read more...

Stevens-Johnson syndrome and toxic epidermal necrolysis: consequence of treatment of an emerging pathogen.

30 Jul 2009 We report a case of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection. Although ... Read more...

Latest indexed articles for 'Stevens-Johnson Syndrome - Chemically induced'

These are the very latest articles for this heading:

• Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population. 30 Aug 2009
• High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients. 30 Aug 2009
• Stevens-Johnson syndrome and toxic epidermal necrolysis: consequence of treatment of an emerging pathogen. 30 Jul 2009
• Foreword. Drug allergy and primum non-nocere. 30 Jul 2009
• [Drug patch tests in the investigation of cutaneous adverse drug reactions] 26 Jul 2009
• Stevens-Johnson syndrome induced by combination of imatinib and allopurinol. 9 May 2009
• [Stevens-Johnson syndrome and toxic hepatitis due to esomeprazole] 27 Feb 2009
• Seasonal variation of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with trimethoprim-sulfamethoxazole. 11 Feb 2009
• Oxcarbazepine-induced Stevens-Johnson syndrome: a case report. 30 Jan 2009
• Acute renal failure and its risk factors in Stevens-Johnson syndrome and toxic epidermal necrolysis. 19 Jan 2009
• Allopurinol and the role of uric acid in hypertension. 19 Jan 2009
• Medications as risk factors of Stevens-Johnson syndrome and toxic epidermal necrolysis in children: a pooled analysis. 17 Jan 2009
• Neopterin and C-reactive protein in the course of Stevens-Johnson syndrome: report of a case. 30 Dec 2008
• Pain and palliative care pharmacotherapy literature summaries and analyses. 30 Dec 2008
• A case with Stevens Johnson syndrome triggered by combination of clobazam, lamotrigine, and valproic acid treatment. 30 Dec 2008
• Aggrenox (Asasantin retard)-induced Stevens-Johnson syndrome. 14 Dec 2008
• [Fever and skin lesions in patients treated with phenobarbital] 29 Nov 2008
• Saving the skin from drug-induced detachment. 29 Nov 2008
• Erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis in lenalidomide-treated patients. 29 Nov 2008
• HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis. 30 Oct 2008

See a longer list of these articles.

Technical information about 'Stevens-Johnson Syndrome'

Definition: A variant of bullous erythema multiforme. It ranges from mild skin and mucous membrane lesions to a severe, sometimes fatal systemic disorder. Ocular symptoms include ulcerative conjunctivitis, keratitis, iritis, uveitis, and sometimes blindness. The cause of the disease is unknown.

Descriptor UI: D013262

Alternative terms: Stevens-Johnson Syndrome; Stevens Johnson Syndrome;

Allowable Qualifiers: embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology; blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics;

Tree Number: C07.465.864.500; C17.800.229.400.683; C17.800.865.475.683;

Technical Notes: a sometimes fatal form of erythema multiforme