Stevens-Johnson Syndrome
Research News and Information

Sunday, November 22, 2009

Successful prevention of bacterial endophthalmitis in eyes with the Boston keratoprosthesis.

30 Aug 2009 PURPOSE: To determine the influence of topical vancomycin prophylaxis on the incidence of bacterial endophthalmitis in eyes with a Boston Keratoprosthesis (KPro). METHODS: A retrospective chart review was performed for 255 eyes of 231 patients who ... Read more...

Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population.

30 Aug 2009 OBJECTIVES: Allopurinol, a uric acid lowering drug commonly used for hyperuricemia and gouty arthritis, has been reported as a common cause of severe cutaneous adverse drug reactions (SCAR) including Stevens-Johnson syndrome (SJS) and toxic ... Read more...

High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients.

30 Aug 2009 BACKGROUND: Severe cutaneous adverse reactions (SCARs) are associated with over 200 medicines including lamotrigine, an antiepileptic drug. Previous studies have suggested the involvement of immune mechanisms in the development of drug-induced ... Read more...

Latest indexed articles for 'Stevens-Johnson Syndrome'

These are the very latest articles for this heading:

• Granulysin as a marker for early diagnosis of the Stevens-Johnson syndrome. 4 Oct 2009
• Successful prevention of bacterial endophthalmitis in eyes with the Boston keratoprosthesis. 30 Aug 2009
• Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population. 30 Aug 2009
• High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients. 30 Aug 2009
• Stevens-Johnson syndrome and toxic epidermal necrolysis: consequence of treatment of an emerging pathogen. 30 Jul 2009
• Foreword. Drug allergy and primum non-nocere. 30 Jul 2009
• An update on Stevens-Johnson syndrome and toxic epidermal necrolysis in children. 30 Jul 2009
• [Drug patch tests in the investigation of cutaneous adverse drug reactions] 26 Jul 2009
• Ophthalmic experience with submandibular gland transplantation for severe dry eyes. 29 Jun 2009
• New testing approach in HLA genotyping helps overcome barriers in effective clinical practice. 23 Jun 2009
• Derm diagnoses you can't afford to miss. 30 May 2009
• Acute management of Stevens-Johnson syndrome and toxic epidermal necrolysis to minimize ocular sequelae. 30 May 2009
• [Stevens-Johnson syndrome plus intrahepatic cholestasis caused by clindamycin or chlorpheniramine] 13 May 2009
• Stevens-Johnson syndrome induced by combination of imatinib and allopurinol. 9 May 2009
• [Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center] 29 Apr 2009
• Topical treatment protocol for Stevens-Johnson syndrome and toxic epidermal necrolysis. 29 Apr 2009
• [Analysis of treatments and deceased cases of severe adverse drug reactions--analysis of 46 cases of Stevens-Johnson syndrome and toxic epidermal necrolysis] 29 Apr 2009
• In vivo confocal microscopic evaluation of corneal changes in chronic Stevens-Johnson syndrome and toxic epidermal necrolysis. 29 Apr 2009
• The red eye: evaluation and management. 6 Apr 2009
• Genetic basis for idiosyncratic reactions to antiepileptic drugs. 30 Mar 2009

See a longer list of these articles.

Technical information about 'Stevens-Johnson Syndrome'

Definition: A variant of bullous erythema multiforme. It ranges from mild skin and mucous membrane lesions to a severe, sometimes fatal systemic disorder. Ocular symptoms include ulcerative conjunctivitis, keratitis, iritis, uveitis, and sometimes blindness. The cause of the disease is unknown.

Descriptor UI: D013262

Alternative terms: Stevens-Johnson Syndrome; Stevens Johnson Syndrome;

Allowable Qualifiers: embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology; blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics;

Tree Number: C07.465.864.500; C17.800.229.400.683; C17.800.865.475.683;

Technical Notes: a sometimes fatal form of erythema multiforme