Subcellular Fractions - Drug effects
Research News and Information

Monday, November 23, 2009

Time-dependent exposure of nicotine and smoke modulate ultrasubcellular organelle localization of dopamine D1 and D2 receptors in the rat caudate-putamen.

29 Sep 2009 The correlation of the subcellular localization of dopamine D(1) and D(2) receptors (DA D(1) R, DA D(2) R) with nicotine addiction has not been studied. We demonstrated the ultrasubcellular organelle localization of DA D(1) and D(2) Rs in the ... Read more...

Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels.

28 Sep 2009 PURPOSE: Lens epithelial cell (LEC) apoptosis reduces the formation of posterior capsular opacification (PCO). The involvement of caveolin-1 in the regulation of apoptosis has been previously demonstrated in epithelial cells. In this study, we ... Read more...

Correlations and co-localizations of Hsp70 with XPA, XPG in human bronchial epithelia cells exposed to benzo[a]pyrene.

9 Sep 2009 Benzo[a]pyrene (BaP) is a ubiquitously distributed environmental pollutant known to cause DNA damage, which may be repaired through nucleotide excision repair (NER). The significantly negative correlation between Hsp70 levels and the level of DNA ... Read more...

Latest indexed articles for 'Subcellular Fractions - Drug effects'

These are the very latest articles for this heading:

• Time-dependent exposure of nicotine and smoke modulate ultrasubcellular organelle localization of dopamine D1 and D2 receptors in the rat caudate-putamen. 29 Sep 2009
• Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels. 28 Sep 2009
• Correlations and co-localizations of Hsp70 with XPA, XPG in human bronchial epithelia cells exposed to benzo[a]pyrene. 9 Sep 2009
• Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats. 9 Sep 2009
• BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution. 25 Aug 2009
• Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. 13 Aug 2009
• Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. 8 Aug 2009
• Highly efficient multicistronic lentiviral vectors with peptide 2A sequences. 30 Jul 2009
• Evidence supporting the existence of L-arginine-dependent nitric oxide synthase activity in plants. 27 Jul 2009
• NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. 27 Jul 2009
• Intra- versus extracellular effects of microglia-derived cysteine proteases in a conditioned medium transfer model. 15 Jul 2009
• Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia. 12 Jul 2009
• Function of the tryptophan metabolite, L-kynurenine, in human corneal endothelial cells. 6 Jul 2009
• Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists. 6 Jul 2009
• Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells. 29 Jun 2009
• cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium. 20 Jun 2009
• A novel cation-dependent O-methyltransferase involved in anthocyanin methylation in grapevine. 10 Jun 2009
• Toxicological evaluation of pomegranate seed oil. 30 May 2009
• Inhibitory mechanism of saponins derived from roots of Platycodon grandiflorum on anaphylactic reaction and IgE-mediated allergic response in mast cells. 30 May 2009
• Novel application of fluorescence lifetime and fluorescence microscopy enables quantitative access to subcellular dynamics in plant cells. 25 May 2009

See a longer list of these articles.

Technical information about 'Subcellular Fractions'

Definition: Components of a cell produced by various separation techniques which, though they disrupt the delicate anatomy of a cell, preserve the structure and physiology of its functioning constituents for biochemical and ultrastructural analysis. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p163)

Descriptor UI: D013347

Alternative terms: Subcellular Fractions; Fraction, Subcellular; Fractions, Subcellular; Subcellular Fraction;

Related Mesh Headings: Cell Fractionation;

Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.284.835;

Online Note: use SUBCELLULAR FRACTIONS to search HOMOGENATES 1966

History Note: 72; HOMOGENATES was Prov 1964-66

Technical Notes: NIM; A 11 qualif except /cytol