Sulfonamides
Research News and Information

Monday, November 23, 2009

Efficacy of aggressive lipid controlling therapy for preventing saphenous vein graft disease.

30 Oct 2009 BACKGROUND: We assessed the efficacy of aggressive lipid controlling therapy (ALCT), which maintains low-density lipoprotein cholesterol (LDL-C) below to 80 mg/dL and LDL/high-density lipoprotein cholesterol (HDL-C) ratio less than 1.5 for ... Read more...

Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling.

19 Oct 2009 Prostaglandin E(2) (PGE(2)) mediates the masculinization of adult sex behavior in rats in response to the surge in serum testosterone at approximately birth. Measures of behavioral masculinization correlate with a twofold increase in spinophilin ... Read more...

Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.

6 Oct 2009 Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most prescribed medications, although the chronic use of such pharmacological agents is commonly associated with numerous side effects. The demonstration that the use of COX-2 ... Read more...

Latest indexed articles for 'Sulfonamides'

These are the very latest articles for this heading:

• Alpha1-adrenergic blockers and intraoperative floppy-iris syndrome. 30 Oct 2009
• Efficacy of aggressive lipid controlling therapy for preventing saphenous vein graft disease. 30 Oct 2009
• Tom MacDonald replies to Marisa de Andrade. 19 Oct 2009
• Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling. 19 Oct 2009
• Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors. 6 Oct 2009
• Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes. 6 Oct 2009
• Identification of novel indanylsulfonamide guanylhydrazones as potent 5-HT6 serotonin receptor antagonists. 6 Oct 2009
• Differential effects of non-steroidal anti-inflammatory drugs on mitochondrial dysfunction during oxidative stress. 29 Sep 2009
• Delayed onset nodules from liquid injectable silicone: report of a case, evaluation of associated histopathology and results of treatment with minocycline and celocoxib. 29 Sep 2009
• Effects of a 3-month course of rosuvastatin in patients with systemic lupus erythematosus. 29 Sep 2009
• Effect of the HMG-CoA reductase inhibitor rosuvastatin on early chronic kidney injury in obese zucker rats fed with an atherogenic diet. 29 Sep 2009
• Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs. 29 Sep 2009
• T cell receptor signaling induced by an analog peptide of type II collagen requires activation of Syk. 29 Sep 2009
• Crystallographic analysis of bacterial signal peptidase in ternary complex with arylomycin A2 and a beta-sultam inhibitor. 27 Sep 2009
• Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity. 22 Sep 2009
• Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress. 16 Sep 2009
• Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78). 11 Sep 2009
• Serotonin targets inhibitory synapses to induce modulation of network functions. 10 Sep 2009
• Tamsulosin and ophthalmic adverse events after cataract surgery. 7 Sep 2009
• Tamsulosin and ophthalmic adverse events after cataract surgery. 7 Sep 2009

See a longer list of these articles.

Technical information about 'Sulfonamides'

Definition: A group of compounds that contain the structure SO2NH2. Members of this group, also known as sulfa drugs, are derivatives of sulfanilamide, which competitively inhibit folic acid synthesis in microorganisms, and are bacteriostatic. They have been largely supplanted by more effective and less toxic antibiotics. (From Dorland, 28th ed)

Registry Number: 0

Descriptor UI: D013449

Alternative terms: Sulfonamides; Sulfonamide Mixtures; Mixtures, Sulfonamide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.065.884; D02.886.590.700;

Online Note: use SULFONAMIDES to search SULFONAMIDE MIXTURES 1966-79

History Note: SULFONAMIDE MIXTURES was heading 1963-79