Sulpiride - Pharmacology
Research News and Information

Sunday, November 22, 2009

Presynaptic action of neurotensin on dopamine release through inhibition of D(2) receptor function.

12 Aug 2009 BACKGROUND: Neurotensin (NT) is known to act on dopamine (DA) neurons at the somatodendritic level to regulate cell firing and secondarily enhance DA release. In addition, anatomical and indirect physiological data suggest the presence of NT ... Read more...

Dopaminergic modulation of olfactory bulb processing affects odor discrimination learning in rats.

30 Jul 2009 Olfactory behavioral studies have shown that, when modulated through systemic injections, D1 and D2 receptors have opposing effects on odor discrimination learning. In the present study, cannulated male Sprague-Dawley rats were used to investigate ... Read more...

[Effect of sulpiride on immobility reflex and pinch-induced catalepsy in CBA/Lac male mice with various social status]

29 Jun 2009 This study was aimed to determine the effect of D2/D3 receptor antagonist sulpiride on the expression of immobility reflex ("pinch-test") and pinch-induced catalepsy ("bar-test") of CBA/Lac male mice depending on their social status ("aggressors" ... Read more...

Latest indexed articles for 'Sulpiride - Pharmacology'

These are the very latest articles for this heading:

• Presynaptic action of neurotensin on dopamine release through inhibition of D(2) receptor function. 12 Aug 2009
• Dopaminergic modulation of olfactory bulb processing affects odor discrimination learning in rats. 30 Jul 2009
• [Effect of sulpiride on immobility reflex and pinch-induced catalepsy in CBA/Lac male mice with various social status] 29 Jun 2009
• Profound changes in dopaminergic neurotransmission in the prefrontal cortex in response to flattening of the diurnal glucocorticoid rhythm: implications for bipolar disorder. Jun 2009
• Targeting cognition in schizophrenia research: from etiology to treatment. 30 May 2009
• Effects of cannabinoids infused into the dorsal hippocampus upon memory formation in 3-days apomorphine-treated rats. 16 May 2009
• Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. 5 May 2009
• Evaluation of antidepressant like property of amisulpride per se and its comparison with fluoxetine and olanzapine using forced swimming test in albino mice. 29 Apr 2009
• Neurocognitive effectiveness of haloperidol, risperidone, and olanzapine in first-episode psychosis: a randomized, controlled 1-year follow-up comparison. 29 Apr 2009
• Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo. 30 Mar 2009
• Amisulpride treatment for clozapine-induced sialorrhea. 30 Mar 2009
• A comparative study on the effects of the benzodiazepine midazolam and the dopamine agents, apomorphine and sulpiride, on rat behavior in the two-way avoidance test. 30 Mar 2009
• Dopamine released by dendritic cells polarizes Th2 differentiation. 28 Mar 2009
• Genotoxicity of the neurotransmitter dopamine in vitro. 10 Mar 2009
• D1-receptor impact on neuroplasticity in humans. 23 Feb 2009
• Pharmacological modulation of dopaminergic brain activity and its reflection in spectral frequencies of the rat electropharmacogram. 12 Jan 2009
• [The effect of D2-receptor blockade on the normal and stress-induced activity of the prefrontal cortex neurons in SHR rats] 30 Dec 2008
• Role of dopamine receptors in the ventral tegmental area in conditioned fear. 5 Dec 2008
• Characteristics of prolactin-releasing response to salsolinol (SAL) and thyrotropin-releasing hormone (TRH) in ruminants. 2 Dec 2008
• Cloning, polymorphism, and inhibition of beta-carbonic anhydrase of Helicobacter pylori. 16 Nov 2008

See a longer list of these articles.

Technical information about 'Sulpiride'

Definition: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)

Chemical name: Benzamide, 5-(aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-

Registry Number: 15676-16-1

Descriptor UI: D013469

Alternative terms: Sulpiride; Sulperide; Arminol; Krewel Brand of Sulpiride; Deponerton; Meresa; Vertigo-Meresa; Vertigo Meresa; Dolorgiet Brand of Sulpiride; Desisulpid; Desitin Brand of Sulpiride; Digton; Areu Brand of Sulpiride; Dogmatil; Dolmatil; Sanofi-Synthelabo Brand of Sulpiride; Sanofi Synthelabo Brand of Sulpiride; Allphar Brand of Sulpiride; Eglonyl; Ekilid; Hoechst Brand of Sulpiride; Guastil; Uriach Brand of Sulpiride; Lebopride; Spyfarma Brand of Sulpiride; neogama; vertigo-neogama; vertigo neogama; Hormosan Brand of Sulpiride; Pontiride; Psicofarma Brand of Sulpiride; Psicocen; Centrum Brand of Sulpiride; Sulpitil; Pharmacia Brand of Sulpiride; Sulpivert; Hennig Brand of Sulpiride; Sulpor; Rosemont Brand of Sulpiride; Sulp; Hexal Brand of Sulpiride; Tepavil; Almirall Brand of Sulpiride; Synédil; Erempharma Brand of Sulpiride; Aiglonyl; Fumouzer Brand of Sulpiride;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Dopamine Antagonists; Antidepressive Agents, Second-Generation; Antipsychotic Agents;

Tree Number: D02.065.277.866; D02.241.223.100.120.866;

History Note: 74