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Surface Plasmon Resonance
Research News and Information
Definition of 'Surface Plasmon Resonance'A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding. |
Sunday, November 22, 2009
p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.
29 Nov 2009 
The stress protein p8 is a small, highly basic, unfolded, and multifunctional protein. We have previously shown that most of its functions are exerted through interactions with other proteins, whose activities are thereby enhanced or repressed. In ... Read more...
Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins.
8 Nov 2009 Polycomb group (PcG) proteins are a special set of repressive transcription factors involved in epigenetic modifications of chromatin. They form two functionally distinct groups of catalytically active complexes: Polycomb repressive complex 1 (PRC1) ... Read more...
Nov 2009 Several different monoclonal antibodies (mAbs) have been actively developed in the field of Alzheimer's disease (AD) for basic science and clinical applications; however, the binding kinetics of many of the mAbs with the beta-amyloid peptides ... Read more...
Latest indexed articles for 'Surface Plasmon Resonance'
These are the very latest articles for this heading:
- p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. 29 Nov 2009
- Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins. 8 Nov 2009
- Surface plasmon resonance binding kinetics of Alzheimer's disease amyloid beta peptide-capturing and plaque-binding monoclonal antibodies. Nov 2009
- Characterization of the CHK1 allosteric inhibitor binding site. 18 Oct 2009
- Efficient near-IR hyperthermia and intense nonlinear optical imaging contrast on the gold nanorod-in-shell nanostructures. 12 Oct 2009
- Novel anti-cancer compounds: structure-based discovery of chemical chaperons for p53. 29 Sep 2009
- Biospecific protein immobilization for rapid analysis of weak protein interactions using self-interaction nanoparticle spectroscopy. 29 Sep 2009
- Cargo binding induces dimerization of myosin VI. 26 Sep 2009
- Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins. 7 Sep 2009
- Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein. 7 Sep 2009
- Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2. 31 Aug 2009
- Kinetic control of TolC recruitment by multidrug efflux complexes. 31 Aug 2009
- Plasmon-induced enhancement in analytical performance based on gold nanoparticles deposited on TiO2 film. 30 Aug 2009
- Short communication: generation of recombinant monoclonal antibodies against an immunodominant HLA-A*2402-restricted HIV type 1 CTL epitope. 30 Aug 2009
- Stability of binary SAMs formed by omega-acid and alcohol functionalized thiol mixtures. 30 Aug 2009
- Cadherin and integrin regulation of epithelial cell migration. 30 Aug 2009
- Surface plasmon resonance imaging for biosensing. 30 Aug 2009
- Engineering the binding properties of the T cell receptor:peptide:MHC ternary complex that governs T cell activity. 30 Aug 2009
- Binding and internalization of Clostridium botulinum C2 toxin. 29 Aug 2009
- Broadly neutralizing anti-HBV antibody binds to non-epitope regions of preS1. 27 Aug 2009
See a longer list of these articles.
Technical information about 'Surface Plasmon Resonance'
Definition: A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Descriptor UI: D020349
Alternative terms: Surface Plasmon Resonance; Plasmon Resonance, Surface; Plasmon Resonances, Surface; Resonance, Surface Plasmon; Resonances, Surface Plasmon; Surface Plasmon Resonances;
Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;
Tree Number: E05.196.890; E05.601.123.700;
History Note: 99
Technical Notes: do not confuse with plasmon, extrachromosomal genetic material