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Synapses - Physiopathology
Research News and Information
Definition of 'Synapses'Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions. |
Sunday, November 22, 2009
30 Jul 1989
The activity of tyrosine hydroxylase (TOH), the rate-limiting enzyme in norepinephrine biosynthesis, was measured in selected sympathetic ganglia to develop a quantitative measure of sympathetic autonomic neuropathy in streptozocin-induced diabetic ... Read more...
30 Aug 1988
The occurrence of synchronous, self-sustaining seizure activity is one of the basic mechanisms underlying epileptic attacks. Using a mathematical model of neuronal network in various simulation experiments carried out in digital computer the ... Read more...
30 Aug 1988
Experiments were conducted to determine whether a consistent pattern of auditory nerve brain-stem evoked synaptic lesion model in cats (elevated levels of the lesion model in cats (elevated levels of the barbiturate thiopental). The ABP in response ... Read more...
Latest indexed articles for 'Synapses - Physiopathology'
These are the very latest articles for this heading:
- Tyrosine hydroxylase activity in sympathetic nervous system of rats with streptozocin-induced diabetes.
30 Jul 1989 - [Study of the mechanisms of the development of epileptic activity in neuronal networks using a simulation model]
30 Aug 1988 - Auditory brain-stem (ABP) and somatosensory evoked potentials (SEP) in an animal model of a synaptic lesion: elevated plasma barbiturate levels.
30 Aug 1988 - Cellular mechanisms of epilepsy: a status report.
8 Jul 1987 - Spasticity.
30 May 1987 - Reversibility of alcohol-related brain damage: clinical and experimental observations.
30 Dec 1986 - The role of interstitial potassium in the generation of low-calcium hippocampal seizures.
30 Dec 1986 - Electrophysiological evidence for a presynaptic mechanism of morphine withdrawal in the neonatal rat spinal cord.
22 Sep 1986 - Recovery potentials following CNS lesions: a brief historical perspective in relation to modern research data on neuroplasticity.
29 Jun 1986 - [Physiopathology of Parkinson's disease]
27 Feb 1986 - Presynaptic inhibition of primary afferents.
30 Dec 1985 - Reflex activity and axonal conduction in the L-7 spinal cord segment following experimental compression trauma.
30 May 1985 - Motoneuron death and motor unit size during embryonic development of the rat.
30 Dec 1983 - Chronic ethanol-induced decreases in the response of dentate granule cells to perforant path input in the rat.
30 Dec 1983 - Repetitive stimulation in the central nervous system.
30 Jul 1983 - Evoked potentials in the clinical neurosciences.
30 Dec 1981 - CNS myelin and synapses in a spontaneous mouse ovarian teratoma showing neural differentiation. An immunohistochemical and electron microscopic study.
29 Apr 1981 - Neuronal mechanisms of seizure initiation.
30 Dec 1979 - A stereological analysis of the neuronal and synaptic content of the frontal and cerebellar cortex of weanling rats undernourished from birth.
29 Jun 1979 - Neuromuscular synapse testing in two cases of suicidal organophosphorous pesticide poisoning.
30 Aug 1978
See a longer list of these articles.
Technical information about 'Synapses'
Definition: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Descriptor UI: D013569
Alternative terms: Synapses; Synapse;
Related Mesh Headings: Synaptic Transmission; Synaptosomes; Gap Junctions;
Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; ultrastructure; ultrasonography; chemistry; virology; genetics;
Tree Number: A08.850; A11.284.149.165.420.780;
Technical Notes: note specifics; IMMUNOLOGICAL SYNAPSES is also available; / physiol: consider also SYNAPTIC TRANSMISSION; do not confuse with SYNAPSIS see CHROMOSOME PAIRING