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Synapses
Research News and Information
Definition of 'Synapses'Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions. |
Saturday, November 07, 2009
Fast synaptic subcortical control of hippocampal circuits.
14 Oct 2009 
Cortical information processing is under state-dependent control of subcortical neuromodulatory systems. Although this modulatory effect is thought to be mediated mainly by slow nonsynaptic metabotropic receptors, other mechanisms, such as direct ... Read more...
14 Oct 2009 An emerging set of methods enables an experimental dialogue with biological systems composed of many interacting cell types--in particular, with neural circuits in the brain. These methods are sometimes called "optogenetic" because they use ... Read more...
Molecular and cellular approaches to memory allocation in neural circuits.
14 Oct 2009 Although memory allocation is a subject of active research in computer science, little is known about how the brain allocates information within neural circuits. There is an extensive literature on how specific types of memory engage different parts ... Read more...
Latest indexed articles for 'Synapses'
These are the very latest articles for this heading:
- Fast synaptic subcortical control of hippocampal circuits. 14 Oct 2009
- The optogenetic catechism. 14 Oct 2009
- Molecular and cellular approaches to memory allocation in neural circuits. 14 Oct 2009
- Immune proteins in brain development and synaptic plasticity. 13 Oct 2009
- MHC class I: an unexpected role in neuronal plasticity. 13 Oct 2009
- Breaking boundaries in neural-immune interactions. 13 Oct 2009
- Input-specific intrasynaptic arrangements of ionotropic glutamate receptors and their impact on postsynaptic responses. 12 Oct 2009
- Convergence of cranial visceral afferents within the solitary tract nucleus. 12 Oct 2009
- Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking. 12 Oct 2009
- Functional properties of synaptic transmission in primary sense organs. 12 Oct 2009
- Axonal transport defects in neurodegenerative diseases. 12 Oct 2009
- Understanding the role of DISC1 in psychiatric disease and during normal development. 12 Oct 2009
- Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition. 4 Oct 2009
- The proportion of synapses formed by the axons of the lateral geniculate nucleus in layer 4 of area 17 of the cat. 29 Sep 2009
- Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. 29 Sep 2009
- N-type calcium channels mediate a GABA(B) presynaptic modulation in the corticostriatal synapse in turtle's paleostriatum augmentatum. 29 Sep 2009
- Interfering with the actin network and its effect on long-term potentiation and synaptic tagging in hippocampal CA1 neurons in slices in vitro. 28 Sep 2009
- AnkyrinG is required to maintain axo-dendritic polarity in vivo. 22 Sep 2009
- Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration. 22 Sep 2009
- High-affinity kainate receptor subunits are necessary for ionotropic but not metabotropic signaling. 22 Sep 2009
See a longer list of these articles.
Technical information about 'Synapses'
Definition: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Descriptor UI: D013569
Alternative terms: Synapses; Synapse;
Related Mesh Headings: Synaptic Transmission; Synaptosomes; Gap Junctions;
Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; ultrastructure; ultrasonography; chemistry; virology; genetics;
Tree Number: A08.850; A11.284.149.165.420.780;
Technical Notes: note specifics; IMMUNOLOGICAL SYNAPSES is also available; / physiol: consider also SYNAPTIC TRANSMISSION; do not confuse with SYNAPSIS see CHROMOSOME PAIRING