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Synaptic Transmission - Physiology
Research News and Information
Definition of 'Synaptic Transmission'The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES. |
Saturday, November 21, 2009
2 Nov 2009
Neuroligins are cell adhesion molecules involved in synapse formation and/or function. Neurons express four neuroligins (NL1-NL4), of which NL1 is specific to excitatory and NL2 to inhibitory synapses. Excitatory and inhibitory synapses include ... Read more...
30 Oct 2009
OBJECTIVE: To describe structural and biochemical evidence from postmortem brains that implicates the reciprocal connections between the mediodorsal thalamic nucleus and the prefrontal cortex in cognitive symptoms of schizophrenia. METHOD: The ... Read more...
Regulation of trigeminal respiratory motor activity in the brainstem.
30 Oct 2009
The trigeminal motor system participates in the control of respiration as well as suckling and mastication. However, the central mechanism underlying respiratory activity in trigeminal motoneurons is not well-understood. In this study, we aimed to ... Read more...
Latest indexed articles for 'Synaptic Transmission - Physiology'
These are the very latest articles for this heading:
- Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.
2 Nov 2009 - Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop.
30 Oct 2009 - Regulation of trigeminal respiratory motor activity in the brainstem.
30 Oct 2009 - Astrocyte-neuron interactions: implications for epilepsy.
18 Oct 2009 - KIF5B motor adaptor syntabulin maintains synaptic transmission in sympathetic neurons.
12 Oct 2009 - Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity.
12 Oct 2009 - Functional properties of synaptic transmission in primary sense organs.
12 Oct 2009 - Extrasynaptic GABAA receptors: form, pharmacology, and function.
12 Oct 2009 - Experience-induced neural circuits that achieve high capacity.
29 Sep 2009 - Stimulus-dependent correlations and population codes.
29 Sep 2009 - Correlation between eigenvalue spectra and dynamics of neural networks.
29 Sep 2009 - Receptive field self-organization in a model of the fine structure in v1 cortical columns.
29 Sep 2009 - A bushy cell network in the rat ventral cochlear nucleus.
29 Sep 2009 - Positron emission tomography measures of endogenous opioid neurotransmission and impulsiveness traits in humans.
29 Sep 2009 - Bidirectional signaling of ErbB and Eph receptors at synapses.
27 Sep 2009 - NMDA receptor phosphorylation at a site affected in schizophrenia controls synaptic and behavioral plasticity.
21 Sep 2009 - A novel postsynaptic group II metabotropic glutamate receptor role in modulating baroreceptor signal transmission.
21 Sep 2009 - Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish: cellular organization and neurotransmitters.
18 Sep 2009 - PP2A and GSK-3beta act antagonistically to regulate active zone development.
14 Sep 2009 - Dopamine modulation of the in vivo acetylcholine response in the Drosophila mushroom body.
13 Sep 2009
See a longer list of these articles.
Technical information about 'Synaptic Transmission'
Definition: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Descriptor UI: D009435
Alternative terms: Synaptic Transmission; Neurotransmission; Transmission, Synaptic; Transmission, Neural; Neural Transmission;
Related Mesh Headings: Synapses; Gap Junctions;
Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;
Tree Number: G02.111.087.800.850; G02.149.115.800.850; G04.299.880.850; G07.265.337.900; G07.700.240.900; G11.561.600.835;
Online Note: use SYNAPTIC TRANSMISSION to search NEURAL TRANSMISSION 1969-93, NEUROHUMORAL TRANSMISSION 1968, & NERVE TRANSMISSION 1968-93
History Note: 94; was NEURAL TRANSMISSION 1969-93, was NEUROHUMORAL TRANSMISSION 1968; NERVE TRANSMISSION was see NEURAL TRANSMISSION 1969-93
Technical Notes: differentiate entry term NEURAL TRANSMISSION from NEURAL CONDUCTION; consider also NEURAL INHIBITION; neuromuscular transmission = NEUROMUSCULAR JUNCTION / physiol + SYNAPTIC TRANSMISSION