Synaptic Transmission
Research News and Information

Saturday, November 21, 2009

Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.

2 Nov 2009 Neuroligins are cell adhesion molecules involved in synapse formation and/or function. Neurons express four neuroligins (NL1-NL4), of which NL1 is specific to excitatory and NL2 to inhibitory synapses. Excitatory and inhibitory synapses include ... Read more...

Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop.

30 Oct 2009 OBJECTIVE: To describe structural and biochemical evidence from postmortem brains that implicates the reciprocal connections between the mediodorsal thalamic nucleus and the prefrontal cortex in cognitive symptoms of schizophrenia. METHOD: The ... Read more...

Regulation of trigeminal respiratory motor activity in the brainstem.

30 Oct 2009 The trigeminal motor system participates in the control of respiration as well as suckling and mastication. However, the central mechanism underlying respiratory activity in trigeminal motoneurons is not well-understood. In this study, we aimed to ... Read more...

Latest indexed articles for 'Synaptic Transmission'

These are the very latest articles for this heading:

• Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons. 2 Nov 2009
• Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop. 30 Oct 2009
• Regulation of trigeminal respiratory motor activity in the brainstem. 30 Oct 2009
• Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop. 27 Oct 2009
• Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey. 19 Oct 2009
• Astrocyte-neuron interactions: implications for epilepsy. 18 Oct 2009
• KIF5B motor adaptor syntabulin maintains synaptic transmission in sympathetic neurons. 12 Oct 2009
• Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. 12 Oct 2009
• Functional properties of synaptic transmission in primary sense organs. 12 Oct 2009
• Extrasynaptic GABAA receptors: form, pharmacology, and function. 12 Oct 2009
• Cocaine exposure in utero alters synaptic plasticity in the medial prefrontal cortex of postnatal rats. 5 Oct 2009
• Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. 5 Oct 2009
• Experience-induced neural circuits that achieve high capacity. 29 Sep 2009
• Stimulus-dependent correlations and population codes. 29 Sep 2009
• Correlation between eigenvalue spectra and dynamics of neural networks. 29 Sep 2009
• Receptive field self-organization in a model of the fine structure in v1 cortical columns. 29 Sep 2009
• A bushy cell network in the rat ventral cochlear nucleus. 29 Sep 2009
• Differential effects of topiramate on prefrontal glutamatergic transmission when combined with raclopride or clozapine. 29 Sep 2009
• Positron emission tomography measures of endogenous opioid neurotransmission and impulsiveness traits in humans. 29 Sep 2009
• DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Synaptic Transmission'

Definition: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.

Descriptor UI: D009435

Alternative terms: Synaptic Transmission; Neurotransmission; Transmission, Synaptic; Transmission, Neural; Neural Transmission;

Related Mesh Headings: Synapses; Gap Junctions;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.087.800.850; G02.149.115.800.850; G04.299.880.850; G07.265.337.900; G07.700.240.900; G11.561.600.835;

Online Note: use SYNAPTIC TRANSMISSION to search NEURAL TRANSMISSION 1969-93, NEUROHUMORAL TRANSMISSION 1968, & NERVE TRANSMISSION 1968-93

History Note: 94; was NEURAL TRANSMISSION 1969-93, was NEUROHUMORAL TRANSMISSION 1968; NERVE TRANSMISSION was see NEURAL TRANSMISSION 1969-93

Technical Notes: differentiate entry term NEURAL TRANSMISSION from NEURAL CONDUCTION; consider also NEURAL INHIBITION; neuromuscular transmission = NEUROMUSCULAR JUNCTION / physiol + SYNAPTIC TRANSMISSION