Systems Biology
Research News and Information

Saturday, November 21, 2009

Stem cell biology meets systems biology.

30 Oct 2009 Stem cells and their descendents are the building blocks of life. How stem cell populations guarantee their maintenance and/or self-renewal, and how individual stem cells decide to transit from one cell stage to another to generate different cell ... Read more...

Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential?

29 Sep 2009 The ideal microorganism for biofuel production will possess high substrate utilization and processing capacities, fast and deregulated pathways for sugar transport, good tolerance to inhibitors and product, and high metabolic fluxes and will produce ... Read more...

Three-dimensional structural view of the central metabolic network of Thermotoga maritima.

16 Sep 2009 Metabolic pathways have traditionally been described in terms of biochemical reactions and metabolites. With the use of structural genomics and systems biology, we generated a three-dimensional reconstruction of the central metabolic network of the ... Read more...

Latest indexed articles for 'Systems Biology'

These are the very latest articles for this heading:

• Stem cell biology meets systems biology. 30 Oct 2009
• Journal club. An evolutionary biologist compares genomic complexity to modern art. 6 Oct 2009
• Philosophy of science. The coordinates of truth. 30 Sep 2009
• Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential? 29 Sep 2009
• Three-dimensional structural view of the central metabolic network of Thermotoga maritima. 16 Sep 2009
• Disease signatures are robust across tissues and experiments. 13 Sep 2009
• Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism. 13 Sep 2009
• Evidence for a major role of antisense RNAs in cyanobacterial gene regulation. 13 Sep 2009
• A simple and efficient algorithm for genome-wide homozygosity analysis in disease. 13 Sep 2009
• Mechanics in biology: cells and tissues. 11 Sep 2009
• Systems biology of stem cell fate and cellular reprogramming. 7 Sep 2009
• Evolving from reductionism to holism: is there a future for systems medicine? 31 Aug 2009
• Comparative systems biology across an evolutionary gradient within the Shewanella genus. 30 Aug 2009
• The systems biology-based argument for taking a bold step in chemoprophylaxis of sickle vasculopathy. 30 Aug 2009
• A decade of molecular pathogenomic analysis of group A Streptococcus. 30 Aug 2009
• Working towards an exegesis for lipids in biology. 30 Aug 2009
• Applying mass spectrometry-based proteomics to genetics, genomics and network biology. 30 Aug 2009
• Multivariate statistical analysis applied to an IL6 signal transduction model in hepatocytes. 28 Aug 2009
• Strong inference for systems biology. 26 Aug 2009
• Simplified yet highly accurate enzyme kinetics for cases of low substrate concentrations. 26 Aug 2009

See a longer list of these articles.

Technical information about 'Systems Biology'

Definition: Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.

Descriptor UI: D049490

Alternative terms: Systems Biology; Biology, Systems;

Related Mesh Headings: Systems Theory;

Allowable Qualifiers: classification; economics; education; history; instrumentation; legislation & jurisprudence; manpower; methods; organization & administration; standards; trends; statistics & numerical data; ethics;

Tree Number: H01.158.273.180.800;

History Note: 2005