T-Lymphocytes - Immunology
Research News and Information

Tuesday, November 24, 2009

The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells.

13 Nov 2009 Cyclin-A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor-associated genes potentially are useful targets for cancer immunotherapy. However, ... Read more...

Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.

3 Nov 2009 BACKGROUND: Vulvar intraepithelial neoplasia is a chronic disorder caused by high-risk types of human papillomavirus (HPV), most commonly HPV type 16 (HPV-16). Spontaneous regression occurs in less than 1.5% of patients, and the rate of recurrence ... Read more...

In vivo major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells is regulated by gammadelta T and NK cells during the early steps of tumor growth.

31 Oct 2009 Cell surface expression of MHC class I molecules by tumor cells is determinant in the interplay between tumor cells and the immune system. Nevertheless, the mechanisms which regulate MHCI expression on tumor cells are not clear. We previously showed ... Read more...

Latest indexed articles for 'T-Lymphocytes - Immunology'

These are the very latest articles for this heading:

• The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. 13 Nov 2009
• Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. 3 Nov 2009
• In vivo major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells is regulated by gammadelta T and NK cells during the early steps of tumor growth. 31 Oct 2009
• Effects of lipopolysaccharide on the induction of mixed chimerism in cyclophosphamide-induced tolerance. 30 Oct 2009
• The cellular and molecular immune response of the weanling piglet to staphylococcal enterotoxin B. 30 Oct 2009
• Dendritic cell transfected with secondary lymphoid-tissue chemokine and/or interleukin-2 gene-enhanced cytotoxicity of T-lymphocyte in human bladder tumor cell S in vitro. 30 Oct 2009
• Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial. 30 Oct 2009
• "MIATA"-minimal information about T cell assays. 14 Oct 2009
• Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction. 13 Oct 2009
• TCR down-regulation controls T cell homeostasis. 13 Oct 2009
• Recombination signal sequence-associated restriction on TCRdelta gene rearrangement affects the development of tissue-specific gammadelta T cells. 13 Oct 2009
• Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells. 13 Oct 2009
• TCR signal transduction: opening the black box. 13 Oct 2009
• Porphyromonas gingivalis fimbriae induce unique dendritic cell subsets via Toll-like receptor 2. 5 Oct 2009
• Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. 4 Oct 2009
• Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma. 3 Oct 2009
• An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. 2 Oct 2009
• Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase. 29 Sep 2009
• Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development. 29 Sep 2009
• How suppressor cells led to anergy, costimulation, and beyond. 29 Sep 2009

See a longer list of these articles.

Technical information about 'T-Lymphocytes'

Definition: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor UI: D013601

Alternative terms: T-Lymphocytes; T Lymphocytes; T-Lymphocyte; T-Cells; T Cells; T-Cell; Thymus-Dependent Lymphocytes; Lymphocyte, Thymus-Dependent; Lymphocytes, Thymus-Dependent; Thymus Dependent Lymphocytes; Thymus-Dependent Lymphocyte;

Related Mesh Headings: Immunity, Cellular; Lymphocyte Cooperation; CD4-CD8 Ratio;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.118.637.555.567.569; A15.145.229.637.555.567.569; A15.382.490.555.567.569;

History Note: 1990 (1973)

Technical Notes: general; prefer specifics; subpopulations: coordinate T-LYMPHOCYTE SUBSETS (IM) with specific T-LYMPHOCYTE (IM)