T-Lymphocytes - Metabolism
Research News and Information

Sunday, November 22, 2009

Generation of a human immunodeficiency virus type 1 chronically infected monkey B cell line expressing low levels of endogenous TRIM5alpha.

29 Nov 2009 Several innate cellular antiviral factors exist in mammalian cells that prevent the replication of retroviruses. Among them, the tripartite motif protein (TRIM)5alpha has been shown to block human immunodeficiency virus type 1 (HIV-1) infection in ... Read more...

The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells.

13 Nov 2009 Cyclin-A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor-associated genes potentially are useful targets for cancer immunotherapy. However, ... Read more...

Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction.

13 Oct 2009 Increased expression of gangliosides by different tumor types including renal cell carcinoma (RCC) is thought to contribute to the immune suppression observed in cancer patients. In this study, we report an increase in apoptotic T cells from RCC ... Read more...

Latest indexed articles for 'T-Lymphocytes - Metabolism'

These are the very latest articles for this heading:

• Generation of a human immunodeficiency virus type 1 chronically infected monkey B cell line expressing low levels of endogenous TRIM5alpha. 29 Nov 2009
• The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. 13 Nov 2009
• Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction. 13 Oct 2009
• TCR down-regulation controls T cell homeostasis. 13 Oct 2009
• Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. 13 Oct 2009
• Adaptive immunity in hepatocellular carcinoma: prognostic and therapeutic implications. 29 Sep 2009
• Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase. 29 Sep 2009
• How suppressor cells led to anergy, costimulation, and beyond. 29 Sep 2009
• Detection of clonal T cells in the circulation of patients with nephrogenic systemic fibrosis. 29 Sep 2009
• Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. 29 Sep 2009
• Regions of differences encoded antigens as targets for immunodiagnosis of tuberculosis in humans. 29 Sep 2009
• Endogenous Jmjd6 gene product is expressed at the cell surface and regulates phagocytosis in immature monocyte-like activated THP-1 cells. 29 Sep 2009
• Costimulatory pathways in multiple sclerosis: distinctive expression of PD-1 and PD-L1 in patients with different patterns of disease. 28 Sep 2009
• Role of TL1A in the pathogenesis of rheumatoid arthritis. 26 Sep 2009
• Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking Kawasaki disease. 26 Sep 2009
• Pseudolymphoma of the liver associated with primary biliary cirrhosis: a case report and review of literature. 26 Sep 2009
• Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice. 23 Sep 2009
• Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells. 15 Sep 2009
• Radiolabeled humanized anti-CD3 monoclonal antibody visilizumab for imaging human T-lymphocytes. 14 Sep 2009
• Insulin teaches a new lesson in tolerance. 14 Sep 2009

See a longer list of these articles.

Technical information about 'T-Lymphocytes'

Definition: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor UI: D013601

Alternative terms: T-Lymphocytes; T Lymphocytes; T-Lymphocyte; T-Cells; T Cells; T-Cell; Thymus-Dependent Lymphocytes; Lymphocyte, Thymus-Dependent; Lymphocytes, Thymus-Dependent; Thymus Dependent Lymphocytes; Thymus-Dependent Lymphocyte;

Related Mesh Headings: Immunity, Cellular; Lymphocyte Cooperation; CD4-CD8 Ratio;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.118.637.555.567.569; A15.145.229.637.555.567.569; A15.382.490.555.567.569;

History Note: 1990 (1973)

Technical Notes: general; prefer specifics; subpopulations: coordinate T-LYMPHOCYTE SUBSETS (IM) with specific T-LYMPHOCYTE (IM)