T-Lymphocytes - Pathology
Research News and Information

Sunday, November 22, 2009

Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection.

29 Nov 2009 X-linked lymphoproliferative disease (XLP) is an immunodeficiency caused by defects in the adaptor molecule SAP. The manifestations of XLP generally occur following Epstein-Barr virus (EBV) infection and include fulminant mononucleosis, ... Read more...

Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus.

29 Sep 2009 TNF, lymphotoxin (LT)-alpha, LT-beta and LIGHT are members of a larger superfamily of TNF-related cytokines that can cross-utilize several receptors. Although LIGHT has been implicated in thymic development and function, the role of TNF and LT ... Read more...

Cell-autonomous role of EphB2 and EphB3 receptors in the thymic epithelial cell organization.

29 Sep 2009 The role of EphB2 and EphB3 in the organization of thymic epithelial cells has been studied in EphB-deficient fetal thymus lobes grafted under the kidney capsule of WT mice. The deficient lobes, as compared with WT ones, showed altered distribution ... Read more...

Latest indexed articles for 'T-Lymphocytes - Pathology'

These are the very latest articles for this heading:

• Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection. 29 Nov 2009
• Accelerated thymic atrophy as a result of elevated homeostatic expression of the genes encoded by the TNF/lymphotoxin cytokine locus. 29 Sep 2009
• Cell-autonomous role of EphB2 and EphB3 receptors in the thymic epithelial cell organization. 29 Sep 2009
• Mechanisms of HTLV-1 persistence and transformation. 27 Sep 2009
• Nasal polyp cell populations and fungal-specific peripheral blood lymphocyte proliferation in allergic fungal sinusitis. 30 Aug 2009
• In vivo cytometry of antigen-specific t cells using 19F MRI. 30 Aug 2009
• Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. 30 Aug 2009
• Autoimmunity triggers in the NOD mouse: a role for natural auto-antibody reactivities in type 1 diabetes. 30 Aug 2009
• Flow cytometric evaluation of CD38 expression assists in distinguishing follicular hyperplasia from follicular lymphoma. 30 Aug 2009
• The clonality of CD3+ CD10+ T cells in angioimmunoblastic T cell lymphoma, B cell lymphoma, and reactive lymphoid hyperplasia. 30 Aug 2009
• Obesity accelerates thymic aging. 29 Aug 2009
• Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts. 24 Aug 2009
• Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. 17 Aug 2009
• A high proportion of bone marrow T cells with regulatory phenotype (CD4+CD25hiFoxP3+) in Ewing sarcoma patients is associated with metastatic disease. 13 Aug 2009
• Impaired lung dendritic cell migration and T cell stimulation induced by immunostimulatory oligonucleotides contribute to reduced allergic airway inflammation. 8 Aug 2009
• Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy. Aug 2009
• Eosinophil-associated gastrointestinal disorders with asthma: immunohistochemical analyses. Aug 2009
• Increased T-lymphocyte apoptosis in lupus correlates with disease activity and may be responsible for reduced T-cell frequency: a cross-sectional and longitudinal study. 30 Jul 2009
• In vitro tests in drug hypersensitivity diagnosis. 30 Jul 2009
• The feature of TRGV and TRDV repertoire distribution and clonality in patients with immune thrombocytopenic purpura. 30 Jul 2009

See a longer list of these articles.

Technical information about 'T-Lymphocytes'

Definition: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor UI: D013601

Alternative terms: T-Lymphocytes; T Lymphocytes; T-Lymphocyte; T-Cells; T Cells; T-Cell; Thymus-Dependent Lymphocytes; Lymphocyte, Thymus-Dependent; Lymphocytes, Thymus-Dependent; Thymus Dependent Lymphocytes; Thymus-Dependent Lymphocyte;

Related Mesh Headings: Immunity, Cellular; Lymphocyte Cooperation; CD4-CD8 Ratio;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.118.637.555.567.569; A15.145.229.637.555.567.569; A15.382.490.555.567.569;

History Note: 1990 (1973)

Technical Notes: general; prefer specifics; subpopulations: coordinate T-LYMPHOCYTE SUBSETS (IM) with specific T-LYMPHOCYTE (IM)