T-Lymphocytes
Research News and Information

Monday, November 23, 2009

Generation of a human immunodeficiency virus type 1 chronically infected monkey B cell line expressing low levels of endogenous TRIM5alpha.

29 Nov 2009 Several innate cellular antiviral factors exist in mammalian cells that prevent the replication of retroviruses. Among them, the tripartite motif protein (TRIM)5alpha has been shown to block human immunodeficiency virus type 1 (HIV-1) infection in ... Read more...

Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection.

29 Nov 2009 X-linked lymphoproliferative disease (XLP) is an immunodeficiency caused by defects in the adaptor molecule SAP. The manifestations of XLP generally occur following Epstein-Barr virus (EBV) infection and include fulminant mononucleosis, ... Read more...

The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells.

13 Nov 2009 Cyclin-A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor-associated genes potentially are useful targets for cancer immunotherapy. However, ... Read more...

Latest indexed articles for 'T-Lymphocytes'

These are the very latest articles for this heading:

• Infection of T lymphocytes in non-Asian patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. 13 Dec 2009
• Generation of a human immunodeficiency virus type 1 chronically infected monkey B cell line expressing low levels of endogenous TRIM5alpha. 29 Nov 2009
• Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection. 29 Nov 2009
• The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. 13 Nov 2009
• Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. 3 Nov 2009
• In vivo major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells is regulated by gammadelta T and NK cells during the early steps of tumor growth. 31 Oct 2009
• Effects of lipopolysaccharide on the induction of mixed chimerism in cyclophosphamide-induced tolerance. 30 Oct 2009
• The cellular and molecular immune response of the weanling piglet to staphylococcal enterotoxin B. 30 Oct 2009
• Dendritic cell transfected with secondary lymphoid-tissue chemokine and/or interleukin-2 gene-enhanced cytotoxicity of T-lymphocyte in human bladder tumor cell S in vitro. 30 Oct 2009
• CXCR7 is inducible by HTLV-1 Tax and promotes growth and survival of HTLV-1-infected T cells. 30 Oct 2009
• Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial. 30 Oct 2009
• Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration. 30 Oct 2009
• A homozygous CARD9 mutation in a family with susceptibility to fungal infections. 27 Oct 2009
• "MIATA"-minimal information about T cell assays. 14 Oct 2009
• Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction. 13 Oct 2009
• TCR down-regulation controls T cell homeostasis. 13 Oct 2009
• Recombination signal sequence-associated restriction on TCRdelta gene rearrangement affects the development of tissue-specific gammadelta T cells. 13 Oct 2009
• Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells. 13 Oct 2009
• TCR signal transduction: opening the black box. 13 Oct 2009
• Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. 13 Oct 2009

See a longer list of these articles.

Technical information about 'T-Lymphocytes'

Definition: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor UI: D013601

Alternative terms: T-Lymphocytes; T Lymphocytes; T-Lymphocyte; T-Cells; T Cells; T-Cell; Thymus-Dependent Lymphocytes; Lymphocyte, Thymus-Dependent; Lymphocytes, Thymus-Dependent; Thymus Dependent Lymphocytes; Thymus-Dependent Lymphocyte;

Related Mesh Headings: Immunity, Cellular; Lymphocyte Cooperation; CD4-CD8 Ratio;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.118.637.555.567.569; A15.145.229.637.555.567.569; A15.382.490.555.567.569;

History Note: 1990 (1973)

Technical Notes: general; prefer specifics; subpopulations: coordinate T-LYMPHOCYTE SUBSETS (IM) with specific T-LYMPHOCYTE (IM)