Tabernaemontana
Research News and Information

Saturday, November 21, 2009

Biscarpamontamines A and B, an aspidosperma-iboga bisindole alkaloid and an aspidosperma-aspidosperma bisindole alkaloid, from Tabernaemontana sphaerocarpa.

30 Aug 2009 Two new bisindole alkaloids, biscarpamontamine A (1), possessing an aspidosperma-iboga-type skeleton, and biscarpamontamine B (2), having an aspidosperma-aspidosperma-type skeleton, were isolated from stems of Tabernaemontana sphaerocarpa, and their ... Read more...

Four tetracyclic oxindole alkaloids and a taberpsychine derivative from a Malayan Tabernaemontana.

26 Jul 2009 Four tetracyclic oxindole alkaloids, 7(R)- and 7(S)-geissoschizol oxindole (1 and 2), 7(R),16(R)- and 7(S),16(R)-19(E)-isositsirikine oxindole (3 and 4), in addition to a taberpsychine derivative, N(4)-demethyltaberpsychine (5), were isolated from ... Read more...

Tabernines A-C, beta-carbolines from the leaves of Tabernaemontana elegans.

30 May 2009 Three novel beta-carboline indole alkaloids (1-3) have been isolated from a MeOH extract of the leaves of Tabernaemontana elegans. The structures were established by means of spectroscopic techniques including 2D NMR experiments. Compounds 1 and 2 ... Read more...

Latest indexed articles for 'Tabernaemontana'

These are the very latest articles for this heading:

• Biscarpamontamines A and B, an aspidosperma-iboga bisindole alkaloid and an aspidosperma-aspidosperma bisindole alkaloid, from Tabernaemontana sphaerocarpa. 30 Aug 2009
• Four tetracyclic oxindole alkaloids and a taberpsychine derivative from a Malayan Tabernaemontana. 26 Jul 2009
• Tabernines A-C, beta-carbolines from the leaves of Tabernaemontana elegans. 30 May 2009
• Efficient access to the core of the Strychnos, Aspidosperma and Iboga alkaloids. A short synthesis of norfluorocurarine. 16 Mar 2009
• Seco-tabersonine alkaloids from Tabernaemontana corymbosa. 9 Feb 2009
• Jerantinines A-G, cytotoxic Aspidosperma alkaloids from Tabernaemontana corymbosa. 7 Sep 2008
• Two fast screening methods (GC-MS and TLC-ChEI assay) for rapid evaluation of potential anticholinesterasic indole alkaloids in complex mixtures. 30 Aug 2008
• Studies on cytotoxic, hydroxyl radical scavenging and topoisomerase inhibitory activities of extracts of Tabernaemontana divaricata (L.) R.Br. ex Roem. and Schult. 4 Jun 2008
• The near-death experience. 29 Apr 2008
• Ethnobotany & ethnopharmacology of Tabernaemontana divaricata. 30 Mar 2008
• The near-death experience: a cerebellar method to protect body and soul-lessons from the Iboga healing ceremony in Gabon. 30 Dec 2007
• Determination of ibogaine and noribogaine in biological fluids and hair by LC-MS/MS after Tabernanthe iboga abuse Iboga alkaloids distribution in a drowning death case. 17 Nov 2007
• A thermostable cysteine protease precursor from a tropical plant contains an unusual C-terminal propeptide: cDNA cloning, sequence comparison and molecular modeling studies. 26 Aug 2007
• Leishmanicidal activity of a supercritical fluid fraction obtained from Tabernaemontana catharinensis. 18 Jan 2007
• Ibogaine affects brain energy metabolism. 14 Sep 2006
• Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats. 8 Sep 2006
• Distribution of ibogaine and noribogaine in a man following a poisoning involving root bark of the Tabernanthe iboga shrub. 30 Aug 2006
• Liquid chromatography-electrospray mass spectrometry determination of ibogaine and noribogaine in human plasma and whole blood. Application to a poisoning involving Tabernanthe iboga root. 21 Jun 2006
• Vobasinyl-iboga bisindole alkaloids, potent acetylcholinesterase inhibitors from Tabernaemontana divaricata root. 30 May 2006
• Indole alkaloids from Tabernaemontana australis (Muell. Arg) Miers that inhibit acetylcholinesterase enzyme. 31 May 2005

See a longer list of these articles.

Technical information about 'Tabernaemontana'

Definition: A plant genus of the family APOCYNACEAE that contains bisindole alkaloids and IBOGAINE.

Descriptor UI: D030014

Alternative terms: Tabernaemontana; Tabernanthe iboga; Iboga;

Allowable Qualifiers: adverse effects; anatomy & histology; classification; cytology; drug effects; embryology; enzymology; genetics; growth & development; immunology; metabolism; microbiology; parasitology; physiology; poisoning; radiation effects; toxicity; ultrastructure; chemistry; virology;

Tree Number: B06.388.100.081.888;

History Note: 2002

Technical Notes: coord with specific PLANT COMPONENTS term if pertinent; for use in therapy coord IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATION or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manual 26.29