Testis - Drug effects
Research News and Information

Sunday, November 22, 2009

Calpain inhibitors prevent p38 MAPK activation and germ cell apoptosis after heat stress in pubertal rat testes.

30 Oct 2009 Testicular injuries like torsion or cryptorchidism can cause massive germ cell death, which could have great impact on male reproductive health. In addition, it has been proposed that modern life style, in the form of underwear or sedentary work ... Read more...

Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development.

7 Oct 2009 Common male reproductive abnormalities including cryptorchidism, hypospadias, and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal testis dysfunction during a critical developmental period involving reduced ... Read more...

Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis.

23 Sep 2009 BACKGROUND: Sertoli cell junctional proteins (SCJP) (viz. adhesion, gap and tight junctions) are important for spermatogenesis and perturbations in expression of these proteins are associated with impairments in process of sperm production. ... Read more...

Latest indexed articles for 'Testis - Drug effects'

These are the very latest articles for this heading:

• Calpain inhibitors prevent p38 MAPK activation and germ cell apoptosis after heat stress in pubertal rat testes. 30 Oct 2009
• Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development. 7 Oct 2009
• Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis. 23 Sep 2009
• [Influence of Tripterygium wilfordii on the expression of spermiogenesis related genes Herc4, Ipo11 and Mrto4 in mice] 30 Aug 2009
• [Evidence of toxic effect of a chemical on reproduction ignored] 30 Aug 2009
• Involvement of non-enzymatic antioxidant defenses in the protective effect of diphenyl diselenide on testicular damage induced by cadmium in mice. 3 Aug 2009
• Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats. 30 Jul 2009
• Calcitonin gene-related peptide is a survival factor, inhibiting apoptosis in neonatal rat gubernaculum in vitro. 30 Jul 2009
• Chronic mustard toxicity on the testis: a historical cohort study two decades after exposure. 30 Jul 2009
• Studies with regard to the apoptosis of testicular germ cells in rats fed a diet enriched with polyunsaturated Fatty acids. 30 Jul 2009
• Perfluorononanoic acid induces apoptosis involving the Fas death receptor signaling pathway in rat testis. 27 Jul 2009
• Testicular gene expression profiling following 2-methoxyethanol and 2-ethoxyethanol exposure in male rats reveals abnormal expression of the actin binding protein cortactin in degenerating spermatocytes. 26 Jul 2009
• Prenatal exposure to diesel exhaust particles and effect on the male reproductive system in mice. 22 Jul 2009
• Antioxidative effect of royal jelly in cisplatin-induced testes damage. 15 Jul 2009
• Quercetin protects embryonic chicken spermatogonial cells from oxidative damage intoxicated with 3-methyl-4-nitrophenol in primary culture. 7 Jul 2009
• The in vivo expression of dipeptidyl peptidases 8 and 9. 4 Jul 2009
• Hazardous effect of tannery solid waste leachates on development and reproduction in Drosophila melanogaster: 70kDa heat shock protein as a marker of cellular damage. 30 Jun 2009
• Endocrinal toxicity of industrial solvents--a mini review. 29 Jun 2009
• Hesperidin attenuates benzo[alpha] pyrene-induced testicular toxicity in rats via regulation of oxidant/antioxidant balance. 29 Jun 2009
• A stepwise increase in recombinant human growth hormone dosing during puberty achieves improved pubertal growth: a National Cooperative Growth Study report. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Testis'

Definition: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.

Descriptor UI: D013737

Alternative terms: Testis; Testicles; Testicle; Testes;

Related Mesh Headings: Orchiectomy;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A05.360.444.849; A05.360.576.782; A06.407.312.782;

Technical Notes: torsion = SPERMATIC CORD TORSION; inflammation = ORCHITIS; /abnorm: agenesis or dysgenesis: coord TESTIS /abnorm (IM) with GONADAL DYSGENESIS (IM); /cytol: consider also LEYDIG CELLS; /surg is probably ORCHIECTOMY; excision = ORCHIECTOMY