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Testis
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Definition of 'Testis'

The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.

Common names: Testis; Testicles; Testicle; Testes

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Sunday, November 22, 2009

Normal spermatogenesis in a man with mutant luteinizing hormone.

3 Nov 2009 Men with mutations in LHB, the gene encoding the beta subunit of luteinizing hormone (LHB), have azoospermia with absent or few fetal Leydig cells. We report a mutation in LHB in a man and his sister. The man presented with absence of virilization, ... Read more...


Calpain inhibitors prevent p38 MAPK activation and germ cell apoptosis after heat stress in pubertal rat testes.

30 Oct 2009 Testicular injuries like torsion or cryptorchidism can cause massive germ cell death, which could have great impact on male reproductive health. In addition, it has been proposed that modern life style, in the form of underwear or sedentary work ... Read more...


Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development.

7 Oct 2009 Common male reproductive abnormalities including cryptorchidism, hypospadias, and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal testis dysfunction during a critical developmental period involving reduced ... Read more...

 

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Technical information about 'Testis'

Definition: The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.

Descriptor UI: D013737

Alternative terms: Testis; Testicles; Testicle; Testes;

Related Mesh Headings: Orchiectomy;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A05.360.444.849; A05.360.576.782; A06.407.312.782;

Technical Notes: torsion = SPERMATIC CORD TORSION; inflammation = ORCHITIS; /abnorm: agenesis or dysgenesis: coord TESTIS /abnorm (IM) with GONADAL DYSGENESIS (IM); /cytol: consider also LEYDIG CELLS; /surg is probably ORCHIECTOMY; excision = ORCHIECTOMY

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