Testosterone - Deficiency
Research News and Information

Monday, November 23, 2009

Normal spermatogenesis in a man with mutant luteinizing hormone.

3 Nov 2009 Men with mutations in LHB, the gene encoding the beta subunit of luteinizing hormone (LHB), have azoospermia with absent or few fetal Leydig cells. We report a mutation in LHB in a man and his sister. The man presented with absence of virilization, ... Read more...

Hypogonadism-related symptoms: development and evaluation of an empirically derived self-rating instrument (HRS 'Hypogonadism Related Symptom Scale').

29 Sep 2009 While self-report screening instruments are highly sensitive to hypogonadism in the ageing male, they have lacked specificity as evidenced by low or absent correlations with testosterone. The purpose of this paper was to develop an economical and ... Read more...

Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction.

13 Sep 2009 Obesity is associated with a high prevalence of erectile dysfunction; however, the pathophysiological link between obesity and erectile dysfunction remains poorly understood. In this minireview, we have attempted to evaluate the existing literature ... Read more...

Latest indexed articles for 'Testosterone - Deficiency'

These are the very latest articles for this heading:

• Normal spermatogenesis in a man with mutant luteinizing hormone. 3 Nov 2009
• Hypogonadism-related symptoms: development and evaluation of an empirically derived self-rating instrument (HRS 'Hypogonadism Related Symptom Scale'). 29 Sep 2009
• Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction. 13 Sep 2009
• The metabolic syndrome, testosterone deficiency and erectile dysfunction never come alone. 30 Jul 2009
• Prediction of metabolic syndrome by low serum testosterone levels in men: results from the study of health in Pomerania. 4 Jul 2009
• Welcoming low testosterone as a cardiovascular risk factor. 16 Jun 2009
• [Variations in the concentration of the sex hormone binding globulin is a major factor causing a variation in total testosterone values] 9 Jun 2009
• "Staging the aging" when considering androgen deprivation therapy for older men with prostate cancer. 6 Jun 2009
• The role of testosterone in women. 30 May 2009
• Improved effect of Pycnogenol on impaired spatial memory function in partial androgen deficiency rat model. 30 May 2009
• Temporal trends in testosterone levels and treatment in older men. 30 May 2009
• Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. 18 May 2009
• [Pathogenesis, evaluation and treatment of hypogonadism in men] 29 Apr 2009
• Regulation of ryanodine receptor-mediated Ca(2+) release in vas deferens smooth muscle cells. 29 Apr 2009
• Hormonal changes during menopause. 13 Apr 2009
• Role of testosterone in the treatment of hypoactive sexual desire disorder. 6 Apr 2009
• The dark side of testosterone deficiency: III. Cardiovascular disease. 31 Mar 2009
• [Sexual dysfunction in male: a matter of old age or a warning signal?] 31 Mar 2009
• Testosterone deficiency and Peyronie's disease: pilot data suggesting a significant relationship. 28 Mar 2009
• Evaluation of the effects of cigarette smoking on testosterone levels in adult men. 15 Mar 2009

See a longer list of these articles.

Technical information about 'Testosterone'

Definition: A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

Chemical name: Androst-4-en-17beta-ol-3-one

Registry Number: 58-22-0

Descriptor UI: D013739

Alternative terms: Testosterone; 17-beta-Hydroxy-4-Androsten-3-one; 17 beta Hydroxy 4 Androsten 3 one; Androtop; Dr. Kade Brand of Testosterone; Histerone; Hauck Brand of Testosterone; Sterotate; Ulmer Brand of Testosterone; Sustanon; Androderm; Watson Brand of Testosterone; Faulding Brand of Testosterone; Paladin Brand of Testosterone; AstraZeneca Brand of Testosterone; CEPA Brand of Testosterone; Testoderm; Ortho Brand of Testosterone; Ferring Brand of Testosterone; Testolin; Pasadena Brand of Testosterone; Testopel; Bartor Brand of Testosterone; Testosterone Sulfate; AndroGel; Solvay Brand of Testosterone; Unimed Brand of Testosterone; Schering Brand of Testosterone; 8-Isotestosterone; 8 Isotestosterone; 17-beta-Hydroxy-8 alpha-4-Androsten-3-one; 17 beta Hydroxy 8 alpha 4 Androsten 3 one; Andropatch; SmithKline Beecham Brand of Testosterone; GlaxoSmithKline Brand of Testosterone; Testim; Auxilium Pharmaceuticals Inc. Brand of Testosterone;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Androgens;

Tree Number: D04.808.054.079.429.824; D06.472.334.851.968.984;

History Note: 1963; for SUSTANON use TESTOSTERONE (NM) 1976-2003; /therapeutic use was TESTOSTERONE, THERAPEUTIC 1965

Technical Notes: TESTOSTERONE PROPIONATE is also available