Testosterone - Metabolism
Research News and Information

Sunday, November 22, 2009

Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms.

5 Oct 2009 Anabolic androgenic steroids (AAS) can promote detrimental effects on social behaviors for which GABA type A (GABA(A)) receptor-mediated circuits in the forebrain play a critical role. While all AAS bind to androgen receptors (AR), they may also be ... Read more...

Effects of morphine on testosterone levels in rat C6 glioma cells: modulation by anastrozole.

29 Sep 2009 Rat C6 glioma cells are commonly used to investigate the functions of glial cells. To evaluate the presence of testosterone and its metabolism in rat C6 glioma cells, we cultured them in media with or without the addition of testosterone propionate ... Read more...

Testosterone and unconscious positive priming increase human motivation separately.

21 Sep 2009 Clinical observations suggest that testosterone generates unconscious broad-spectrum motivations to act. It has also been suggested that subliminal positive-priming techniques also unconsciously enhances motivation for action. This ... Read more...

Latest indexed articles for 'Testosterone - Metabolism'

These are the very latest articles for this heading:

• Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. 5 Oct 2009
• Effects of morphine on testosterone levels in rat C6 glioma cells: modulation by anastrozole. 29 Sep 2009
• Testosterone and unconscious positive priming increase human motivation separately. 21 Sep 2009
• Frontal brain oscillatory coupling among men who vary in salivary testosterone levels. 25 Aug 2009
• Effects of Ramadan fasting on physical performance and metabolic, hormonal, and inflammatory parameters in middle-distance runners. 30 Jul 2009
• Perfluorononanoic acid induces apoptosis involving the Fas death receptor signaling pathway in rat testis. 27 Jul 2009
• Effects of aggressive encounters on plasma corticosteroid-binding globulin and its ligands in white-crowned sparrows. 6 Jul 2009
• Testosterone's short-term positive effect on luteinizing-hormone secretory-burst mass and its negative effect on secretory-burst frequency are attenuated in middle-aged men. 5 Jul 2009
• Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects. 29 Jun 2009
• Hippocampal lesions impair spatial memory performance, but not song--a developmental study of independent memory systems in the zebra finch. 29 Jun 2009
• Individual variations of serum testosterone in patients with prostate cancer receiving androgen deprivation therapy. Commentary. 29 Jun 2009
• In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients. 29 Jun 2009
• Reduced endothelial progenitor cell number and function in inflammatory bowel disease: a possible link to the pathogenesis. 28 Jun 2009
• Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4. 24 Jun 2009
• Key targets of hormonal treatment of prostate cancer. Part 1: the androgen receptor and steroidogenic pathways. 22 Jun 2009
• Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: proliferative and inflammatory disorders and a possible role of androgens. 19 Jun 2009
• Smoking affects womens' sex hormone-regulated body form. 16 Jun 2009
• Moving beyond dichotomies in research on oral contraceptives: a comment on Edwards and O'Neal. 10 Jun 2009
• Testosterone, sex hormone-binding globulin and free androgen index among adult women: chronological and ovarian aging. 9 Jun 2009
• High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice. 9 Jun 2009

See a longer list of these articles.

Technical information about 'Testosterone'

Definition: A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.

Chemical name: Androst-4-en-17beta-ol-3-one

Registry Number: 58-22-0

Descriptor UI: D013739

Alternative terms: Testosterone; 17-beta-Hydroxy-4-Androsten-3-one; 17 beta Hydroxy 4 Androsten 3 one; Androtop; Dr. Kade Brand of Testosterone; Histerone; Hauck Brand of Testosterone; Sterotate; Ulmer Brand of Testosterone; Sustanon; Androderm; Watson Brand of Testosterone; Faulding Brand of Testosterone; Paladin Brand of Testosterone; AstraZeneca Brand of Testosterone; CEPA Brand of Testosterone; Testoderm; Ortho Brand of Testosterone; Ferring Brand of Testosterone; Testolin; Pasadena Brand of Testosterone; Testopel; Bartor Brand of Testosterone; Testosterone Sulfate; AndroGel; Solvay Brand of Testosterone; Unimed Brand of Testosterone; Schering Brand of Testosterone; 8-Isotestosterone; 8 Isotestosterone; 17-beta-Hydroxy-8 alpha-4-Androsten-3-one; 17 beta Hydroxy 8 alpha 4 Androsten 3 one; Andropatch; SmithKline Beecham Brand of Testosterone; GlaxoSmithKline Brand of Testosterone; Testim; Auxilium Pharmaceuticals Inc. Brand of Testosterone;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Androgens;

Tree Number: D04.808.054.079.429.824; D06.472.334.851.968.984;

History Note: 1963; for SUSTANON use TESTOSTERONE (NM) 1976-2003; /therapeutic use was TESTOSTERONE, THERAPEUTIC 1965

Technical Notes: TESTOSTERONE PROPIONATE is also available