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Thiazoles - Pharmacology
Research News and Information
Saturday, November 21, 2009
29 Nov 2009 
Stage 4 neuroblastoma (NB) is a devastating childhood cancer whose poor outcome has remained essentially unchanged in the last 20 years. Receptor tyrosine kinases have important roles in the control of proliferation, differentiation and apoptosis of ... Read more...
Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance.
6 Oct 2009 We report here that nitazoxanide (NTZ) and its active metabolite kill replicating and nonreplicating M. tuberculosis at low microg/mL levels. NTZ appears to evade resistance, as we were unable to recover resistant colonies, using up to 10(12) colony ... Read more...
29 Sep 2009 Agonists of the peroxisome proliferator activated receptor gamma (PPARgamma) have been shown to reduce inflammatory responses in several animal models of neurological diseases and conditions and to reduce amyloid burden in transgenic mice expressing ... Read more...
Latest indexed articles for 'Thiazoles - Pharmacology'
These are the very latest articles for this heading:
- Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. 29 Nov 2009
- Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance. 6 Oct 2009
- A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease. 29 Sep 2009
- Inhibitors selective for mycobacterial versus human proteasomes. 14 Sep 2009
- 2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization. 8 Sep 2009
- Pharmacological properties and clinical efficacy of dasatinib hydrate (Sprycel), an anticancer drug for chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.
30 Aug 2009 - Gold nanoparticles stabilized by thermosensitive diblock copolymers of poly(ethylene glycol) and polyphosphoester. 30 Aug 2009
- Effects of peritoneal fluid from endometriosis patients on interferon-gamma-induced protein-10 (CXCL10) and interleukin-8 (CXCL8) released by neutrophils and CD4+ T cells. 30 Aug 2009
- Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis. 23 Aug 2009
- Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. 16 Aug 2009
- Characterization of two classes of small molecule inhibitors of Arp2/3 complex. 31 Jul 2009
- Synthesis and biological evaluation of c7-demethyl largazole analogues. 30 Jul 2009
- Aversion- vs fear-inducing properties of 2,4,5-trimethyl-3-thiazoline, a component of fox odor, in comparison with those of butyric acid. 30 Jul 2009
- Ziprasidone vs clozapine in schizophrenia patients refractory to multiple antipsychotic treatments: the MOZART study. 30 Jul 2009
- PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function. 30 Jul 2009
- Novel gene-activated matrix with embedded chitosan/plasmid DNA nanoparticles encoding PDGF for periodontal tissue engineering. 30 Jul 2009
- Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis. 19 Jul 2009
- Class III phosphatidylinositol 4-kinase alpha and beta are novel host factor regulators of hepatitis C virus replication. 13 Jul 2009
- Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment. 12 Jul 2009
- A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells. 10 Jul 2009
See a longer list of these articles.
Technical information about 'Thiazoles'
Registry Number: 0
Descriptor UI: D013844
Alternative terms: Thiazoles;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D02.886.675; D03.383.129.708;
Technical Notes: includes thiazolines, thiazolidines