Thiopental - Administration & dosage
Research News and Information

Sunday, November 22, 2009

The k-in-a-row up-and-down design, revisited.

13 Jun 2009 The percentile-finding experimental design known variously as 'forced-choice fixed-staircase', 'geometric up-and-down' or 'k-in-a-row' (KR) was introduced by Wetherill four decades ago. To date, KR has been by far the most widely used up-and-down ... Read more...

Association of vaginal bleeding and electroconvulsive therapy use in pregnancy.

30 May 2009 Electro-convulsive (ECT) therapy is frequently the treatment of choice in pregnant patients. It has been reported that administration of ECT in pregnancy is safe and effective. However, there are few controlled studies of the effects of ECT on ... Read more...

Effect of endogenous progesterone and oestradiol-17beta on the incidence of gastro-oesophageal reflux and on the barrier pressure during general anaesthesia in the female dog.

10 May 2009 OBJECTIVE: To investigate the potential effect of increased blood progesterone (P(4)) and oestradiol-17beta (E(2)) concentrations on the barrier pressure (BrP) and the incidence of gastro-oesophageal reflux (GOR) in female dogs under general ... Read more...

Latest indexed articles for 'Thiopental - Administration & dosage'

These are the very latest articles for this heading:

• The k-in-a-row up-and-down design, revisited. 13 Jun 2009
• Association of vaginal bleeding and electroconvulsive therapy use in pregnancy. 30 May 2009
• Effect of endogenous progesterone and oestradiol-17beta on the incidence of gastro-oesophageal reflux and on the barrier pressure during general anaesthesia in the female dog. 10 May 2009
• The effect of postoperative fasting on vomiting in children and their assessment of pain. 29 Apr 2009
• Alternative anesthetic management of a child with spastic quadriplegia due to metachromatic leukodystrophy using total intravenous anesthesia. 29 Apr 2009
• A lateral percutaneous technique for stellate ganglion blockade in rats. 29 Apr 2009
• Awareness in children. 30 Jan 2009
• Ventilator-associated pneumonia in patients with cerebral depression. 30 Dec 2008
• The medical-legal quandary of healthcare in capital punishment: an ethical dilemma for the anesthesia provider. 29 Nov 2008
• Issues surrounding lethal injection as a means of capital punishment. 29 Nov 2008
• Atypical postpartum eclampsia: status epilepticus without preeclamptic prodromi. 2 Nov 2008
• Does anesthetic induction for Cesarean section with a combination of ketamine and thiopentone confer any benefits over thiopentone or ketamine alone? A prospective randomized study. 21 Oct 2008
• Is there a role for thiopentone in modern anaesthetic practice? 30 Aug 2008
• [Technique for venous general anesthesia using sodium pentothal] 30 Aug 2008
• Awareness in children: another two cases. 6 May 2008
• Physicians and execution--highlights from a discussion of lethal injection. 21 Jan 2008
• Effects of two different anaesthetics on serum concentrations of cortisol and luteinizing hormone in barrows and gilts. 30 Dec 2007
• Bispectral index monitoring: appreciated but does not affect drug dosing and hypnotic levels. 30 Oct 2007
• [Influence of inhaled nitrous oxide on the induction doses of propofol and thiopental assessed by auditory evoked potentials] 29 Sep 2007
• Thiopental and halothane dose-sparing effects of magnesium sulphate in dogs. 5 Sep 2007

See a longer list of these articles.

Technical information about 'Thiopental'

Definition: A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor analgesic and muscle relaxant properties. Small doses have been shown to be anti-analgesic and lower the pain threshold. (From Martindale, The Extra Pharmacopoeia, 30th ed, p920)

Chemical name: 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-

Registry Number: 76-75-5

Descriptor UI: D013874

Alternative terms: Thiopental; Thiomebumal; Pharmtech Brand of Thiopental Sodium; Thiopentone; Bomathal; Penthiobarbital; Thiopentobarbital; Pentothal; Pentothal Sodico; Merial Brand of Thiopental Sodium; Abbott Brand of Thiopental Sodium; Sodipental; Pisa Brand of Thiopental Sodium; Trapanal; Altana Pharma Brand of Thiopental Sodium; Thiopental Nycomed; Nycomed Brand of Thiopental Sodium; Thiopental Sodium; Tiobarbital Braun; Braun Brand of Thiopental Sodium; Nesdonal; Rhone Merieux Brand of Thiopental Sodium; Thionembutal;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Hypnotics and Sedatives; Anesthetics, Intravenous; GABA Modulators; Anticonvulsants;

Tree Number: D03.383.742.698.253.800.810;