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Thymine
Research News and Information
Monday, November 23, 2009
30 Oct 2009 
Ionizing radiation can induce clustered DNA damage (two or more lesions formed within one to two helical turns of DNA by passage of a single ionization track). Using oligonucleotide constructs containing clustered DNA lesions at defined positions, ... Read more...
Fam83h is associated with intracellular vesicles and ADHCAI.
30 Oct 2009 Defects in FAM83H on human chromosome 8q24.3 cause autosomal-dominant hypocalcified amelogenesis imperfecta (ADHCAI). FAM83H does not encode a recognizable signal peptide, so we predicted that the Fam83h protein functions within the cell. We tested ... Read more...
18 Oct 2009 Oxidative damage to 5-methylcytosine in DNA, followed by deamination, yields thymine glycol (Tg), 5,6-dihydroxy-5,6-dihydrothymine, mispaired with deoxyguanosine. The structure of the 5R Tg.G mismatch pair has been refined using a combination of ... Read more...
Latest indexed articles for 'Thymine'
These are the very latest articles for this heading:
- 5,6-Dihydrothymine impairs the base excision repair pathway of a closely opposed AP site or single-strand break. 30 Oct 2009
- Fam83h is associated with intracellular vesicles and ADHCAI. 30 Oct 2009
- The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. 18 Oct 2009
- Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population. 29 Sep 2009
- Interactions of the "piano-stool" [ruthenium(II) (eta6-arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT study. 30 Aug 2009
- Novel RUNX2 mutations in Chinese individuals with cleidocranial dysplasia. 30 Aug 2009
- Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB. 9 Aug 2009
- Association between IRF6 SNPs and oral clefts in West China. 30 Jul 2009
- Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots. 20 Jul 2009
- Fingerprints of bonding motifs in DNA duplexes of adenine and thymine revealed from circular dichroism: synchrotron radiation experiments and TDDFT calculations. 14 Jul 2009
- The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs. 11 Jul 2009
- Effects of hydration on the proton transfer mechanism in the adenine-thymine base pair. 7 Jul 2009
- Adventitia removal does not modify the alphaID-adrenoceptors response in aorta during hypertension and ageing. 29 Jun 2009
- Quantitative structure-activity relationship study on the anti-HIV-1 activity of novel 6-naphthylthio HEPT analogs. 20 Jun 2009
- Hydrogen bonding between adenine-modified surfaces and terminal thymine-functionalized polystyrene: influence of the surface adenine concentration on polymer recognition. 14 Jun 2009
- Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. Jun 2009
- Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.
23 May 2009 - Cyanide, peroxide and nitric oxide formation in solutions of hydroxyurea causes cellular toxicity and may contribute to its therapeutic potency. 21 May 2009
- Interleukin-2 -330 and 166 gene polymorphisms in relation to aggressive or chronic periodontitis and the presence of periodontopathic bacteria. 16 May 2009
- A miniature condition in Brahman cattle is associated with a single nucleotide mutation within the growth hormone gene. 12 May 2009
See a longer list of these articles.
Technical information about 'Thymine'
Chemical name: 2,4(1H,3H)-Pyrimidinedione, 5-methyl-
Registry Number: 65-71-4
Descriptor UI: D013941
Alternative terms: Thymine; 5-Methyluracil; 5 Methyluracil;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis; physiology;
Tree Number: D03.383.742.698.875.899;
Technical Notes: /biosyn /physiol permitted; thymine deoxyriboside, thymine deoxyribonucleoside = THYMIDINE