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Ticlopidine - Administration & dosage
Research News and Information
Definition of 'Ticlopidine'Ticlopidine is an effective inhibitor of platelet aggregation. The drug has been found to significantly reduce infarction size in acute myocardial infarcts and is an effective antithrombotic agent in arteriovenous fistulas, aorto-coronary bypass grafts, ischemic heart disease, venous thrombosis, and arteriosclerosis. Common names: Ticlopidine; Ticlopidine Hydrochloride; Hydrochloride, Ticlopidine; Ticlodix; Ticlodone; 53-32C; 53 32C; 5332C; Ticlid |
Tuesday, November 24, 2009
4 Oct 2009 
OBJECTIVES: Our aim was to determine whether a 600-mg loading dose of clopidogrel compared with 300 mg results in improved clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary ... Read more...
29 Sep 2009 BACKGROUND: Clopidogrel-naive patients subjected to coronary angiography may be candidates for percutaneous coronary intervention (PCI). Clopidogrel loading with 600 mg at least 2 hours before the procedure is advised for such patients. However, ... Read more...
29 Sep 2009 OBJECTIVE: In peripheral arterial disease (PAD) patients, a limiting factor in the success of percutaneous transluminal angioplasty (PTA) is the development of restenosis secondary to vascular smooth muscle cell (SMC) proliferation. Following ... Read more...
Latest indexed articles for 'Ticlopidine - Administration & dosage'
These are the very latest articles for this heading:
- Role of clopidogrel loading dose in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty: results from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial. 4 Oct 2009
- Timing of clopidogrel loading before percutaneous coronary intervention in clopidogrel-naive patients with stable or unstable angina: a comparison of two strategies. 29 Sep 2009
- Randomized controlled trial of aspirin and clopidogrel versus aspirin and placebo on markers of smooth muscle proliferation before and after peripheral angioplasty. 29 Sep 2009
- Gastrointestinal bleeding in patients with acute coronary syndromes: incidence, predictors, and clinical implications: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. 27 Sep 2009
- Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose the PACA (Proton Pump Inhibitors And Clopidogrel Association) prospective randomized study. 20 Sep 2009
- Challenges in oral antiplatelet therapy: ST-segment elevation myocardial infarction. 5 Sep 2009
- Comparison of bleeding complications with omega-3 fatty acids + aspirin + clopidogrel--versus--aspirin + clopidogrel in patients with cardiovascular disease. 23 Aug 2009
- Cardiovascular disease gets personal.
18 Aug 2009 - The efficacy and safety of prasugrel with and without a glycoprotein IIb/IIIa inhibitor in patients with acute coronary syndromes undergoing percutaneous intervention: a TRITON-TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis In Myocardial Infarction 38) analysis. 16 Aug 2009
- Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3. 30 Jul 2009
- Stent thrombosis up to 3 years after stenting for ST-segment elevation myocardial infarction versus for stable angina--comparison of the effects of drug-eluting versus bare-metal stents. 30 Jul 2009
- Letter by Ryding et al regarding article, "Impact of pretreatment with clopidogrel on initial patency and outcome in patients treated with primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a systematic review". 26 Jul 2009
- Case of the month. Idiopathic dilated cardiomyopathy. 29 Jun 2009
- Rethinking loading dose clopidogrel in light of increased bleeding complications in bypass patients. 28 Jun 2009
- Usefulness of pretreatment with high-dose clopidogrel in patients undergoing primary angioplasty for ST-elevation myocardial infarction. 15 Jun 2009
- Aggressive chronic platelet inhibition with prasugrel and increased cancer risks: revising oral antiplatelet regimens? 2 Jun 2009
- [Clopidogrel plus proton pump inhibitor: is infarct risk increased? (interview by Dr. Thomas Meissner)] 2 Jun 2009
- Prevalence and characteristics of traumatic intracranial hemorrhage in elderly fallers presenting to the emergency department without focal findings. Jun 2009
- Can we override clopidogrel resistance? 31 May 2009
- [Basic examination before clinical examination. That is why it is worthwhile to return to the laboratory] 30 May 2009
See a longer list of these articles.
Technical information about 'Ticlopidine'
Definition: Ticlopidine is an effective inhibitor of platelet aggregation. The drug has been found to significantly reduce infarction size in acute myocardial infarcts and is an effective antithrombotic agent in arteriovenous fistulas, aorto-coronary bypass grafts, ischemic heart disease, venous thrombosis, and arteriosclerosis.
Chemical name: Thieno(3,2-c)pyridine, 5-((2-chlorophenyl)methyl)-4,5,6,7-tetrahydro-
Registry Number: 55142-85-3
Descriptor UI: D013988
Alternative terms: Ticlopidine; Ticlopidine Hydrochloride; Hydrochloride, Ticlopidine; Ticlodix; Ticlodone; 53-32C; 53 32C; 5332C; Ticlid;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Pharmacological Action: Fibrinolytic Agents; Platelet Aggregation Inhibitors;
Tree Number: D02.886.778.834; D03.383.903.834;
History Note: 87