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Tourette Syndrome
Research News and Information
Definition of 'Tourette Syndrome'A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a general medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79) |
Monday, November 23, 2009
Association of intronic variants of the BTBD9 gene with Tourette syndrome.
29 Sep 2009 
OBJECTIVE: To test the association between Tourette syndrome (TS) and genetic variants in genomic loci MEIS1, MAP2K5/LBXCOR1, and BTBD9, for which genome-wide association studies in restless legs syndrome and periodic limb movements during sleep ... Read more...
Streptococcal infection, Tourette syndrome, and OCD: is there a connection?
28 Sep 2009 BACKGROUND: A causal relationship of common streptococcal infections and childhood neuropsychiatric disorders has been postulated. OBJECTIVE: To test the hypothesis of an increased rate of streptococcal infections preceding the onset of ... Read more...
Predictors of early adult outcomes in pediatric-onset obsessive-compulsive disorder.
26 Sep 2009 OBJECTIVE: The aim of this study was to determine the childhood clinical predictors of early adult outcomes in pediatric-onset obsessive-compulsive disorder (OCD) and to assess whether dimensional subtypes of OCD and the presence of comorbid tic ... Read more...
Latest indexed articles for 'Tourette Syndrome'
These are the very latest articles for this heading:
- Perinatal akathisia: implications for pharmacokinetic changes during pregnancy.
30 Oct 2009 - Association of intronic variants of the BTBD9 gene with Tourette syndrome. 29 Sep 2009
- Streptococcal infection, Tourette syndrome, and OCD: is there a connection? 28 Sep 2009
- Predictors of early adult outcomes in pediatric-onset obsessive-compulsive disorder. 26 Sep 2009
- Thinning of the motor-cingulate-insular cortices in siblings concordant for Tourette syndrome. 7 Sep 2009
- Body mass index changes and chronic neuroleptic drug treatment for Tourette syndrome. 30 Aug 2009
- Scientific and ethical issues related to deep brain stimulation for disorders of mood, behavior, and thought. 30 Aug 2009
- Neuroimmune aspects of the pathogenesis of Tourette's syndrome and experience in the use of immunoglobulins in children. 30 Aug 2009
- Issues related to deep brain stimulation for treatment-refractory Tourette's syndrome. 17 Aug 2009
- Tourette syndrome. 30 Jul 2009
- Immunopathogenic mechanisms in tourette syndrome: A critical review. 13 Jul 2009
- [Efficacy of clonidine transdermal patch for treatment of Tourette's syndrome in children] 29 Jun 2009
- Association of SLITRK1 to Gilles de la Tourette Syndrome. 3 Jun 2009
- Prevalence of diagnosed Tourette syndrome in persons aged 6-17 years - United States, 2007.
3 Jun 2009 - Altered fronto-striato-thalamic connectivity in children with Tourette syndrome assessed with diffusion tensor MRI and probabilistic fiber tracking. 30 May 2009
- Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome. 30 May 2009
- COMT gene polymorphism association and drug response in Tourette syndrome. 30 May 2009
- Effects of Ningdong granule on the dopamine system of Tourette's syndrome rat models. 21 May 2009
- Improvement of tics after subthalamic nucleus deep brain stimulation. 17 May 2009
- Determinants of quality of life in children with Gilles de la Tourette syndrome. 13 May 2009
See a longer list of these articles.
Technical information about 'Tourette Syndrome'
Definition: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a general medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
Descriptor UI: D005879
Alternative terms: Tourette Syndrome; Combined Vocal and Multiple Motor Tic Disorder; Gilles de la Tourette Syndrome; Gilles de la Tourette's Disease; Tourette's Syndrome; Syndrome, Tourette's; Tourettes Syndrome; Tic Disorder, Combined Vocal and Multiple Motor; Tourette Disease; Tourette Disorder; Tourette's Disease; Tourettes Disease; Tourette's Disorder; Tourettes Disorder; Combined Multiple Motor and Vocal Tic Disorder; Multiple Motor and Vocal Tic Disorder, Combined;
Related Mesh Headings: Tics;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.228.140.079.898; C10.228.662.825.800; C10.574.500.850; C16.320.400.820; F03.550.825.850;
History Note: 1989(1966)