Toxicity Tests - Methods
Research News and Information

Sunday, November 22, 2009

Liver tissue engineering in the evaluation of drug safety.

29 Sep 2009 Assessment of drug-liver interactions is an integral part of predicting the safety profile of new drugs. Existing model systems range from in vitro cell culture models to FDA-mandated animal tests. Data from these models often fail, however, to ... Read more...

Bioassays for evaluating the water-extractable genotoxic and toxic potential of soils polluted by metal smelters.

29 Sep 2009 Physicochemical analyses of polluted soils are limited in their ability to determine all hazardous compounds, their bioavailability, and their combined effects on living organisms. Bioassays, on the other hand, can evaluate environmental quality ... Read more...

The impact of an additional ecotoxicity test on ecological quality standards.

9 Sep 2009 The present study aims to support decisions on whether or not to perform an extra toxicity test in order to improve environmental quality standards (EQSs). The impact of an additional ecotoxicity test was analyzed by predicting new ecotoxicity ... Read more...

Latest indexed articles for 'Toxicity Tests - Methods'

These are the very latest articles for this heading:

• Liver tissue engineering in the evaluation of drug safety. 29 Sep 2009
• Considerations for reducing the euthanasia procedure in toxicological studies of biopharmaceuticals using non-human primates. 29 Sep 2009
• Bioassays for evaluating the water-extractable genotoxic and toxic potential of soils polluted by metal smelters. 29 Sep 2009
• The impact of an additional ecotoxicity test on ecological quality standards. 9 Sep 2009
• Toxicity testing gets a makeover. 8 Sep 2009
• Twenty-first century approaches to toxicity testing, biomonitoring, and risk assessment: perspectives from the global chemical industry. 30 Aug 2009
• Chemical regulators have overreached. 25 Aug 2009
• Chemical-safety costs uncertain. 25 Aug 2009
• Fridericia peregrinabunda (Enchytraeidae) as a new test species for soil toxicity assessment. 13 Aug 2009
• Putting chemicals on a path to better risk assessment. 5 Aug 2009
• Effect of heavy metal supplementation on local (Allolobophora parva) and exotic (Eisenia fetida) earthworm species: a comparative study. 30 Jul 2009
• TOX 21: new dimensions of toxicity testing. 30 Jul 2009
• RESEARCH ISSUES AND NITIATIVES: agreement could speed reductions in animal use. 30 Jul 2009
• Development of a broad toxicological screening technique for urine using ultra-performance liquid chromatography and time-of-flight mass spectrometry. 26 Jul 2009
• Evaluation of a carp primary hepatocyte culture system for screening chemicals for oestrogenic activity. 14 Jul 2009
• Monoisoamyl dimercaptosuccinic acid abrogates arsenic-induced developmental toxicity in human embryonic stem cell-derived embryoid bodies: comparison with in vivo studies. 13 Jul 2009
• The future of toxicity testing for environmental contaminants. 29 Jun 2009
• A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop. 29 Jun 2009
• Selection of chemicals for the development and evaluation of in vitro methods for skin sensitisation testing. 29 Jun 2009
• Benefits and limits of sediment toxicity tests as an aid to decision-making. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Toxicity Tests'

Definition: An array of tests used to determine the toxicity of a substance to living systems. These include tests on clinical drugs, foods, and environmental pollutants.

Descriptor UI: D018675

Alternative terms: Toxicity Tests; Tests, Toxicity; Test, Toxicity; Toxicity Test;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.940;

History Note: 95

Technical Notes: GEN or unspecified; prefer specifics; used for tests of drugs, food, environ pollutants, etc.; when the test itself is emphasized; coord IM with substance /tox (IM); toxic eff of a specific substance = specific substance /tox; DF: TOX TESTS