Toxicity Tests
Research News and Information

Sunday, November 22, 2009

Liver tissue engineering in the evaluation of drug safety.

29 Sep 2009 Assessment of drug-liver interactions is an integral part of predicting the safety profile of new drugs. Existing model systems range from in vitro cell culture models to FDA-mandated animal tests. Data from these models often fail, however, to ... Read more...

Contact dermatitis caused by sunless tanning treatment with dihydroxyacetone in hairless descendants of Mexican hairless dogs.

29 Sep 2009 Dihydroxyacetone (DHAT) is a color additive that is added to sunless tanning products to produce an artificial tan. Although this agent has been used extensively as safe sunless tanning, no published data are available to judge whether the abuse of ... Read more...

Bioassays for evaluating the water-extractable genotoxic and toxic potential of soils polluted by metal smelters.

29 Sep 2009 Physicochemical analyses of polluted soils are limited in their ability to determine all hazardous compounds, their bioavailability, and their combined effects on living organisms. Bioassays, on the other hand, can evaluate environmental quality ... Read more...

Latest indexed articles for 'Toxicity Tests'

These are the very latest articles for this heading:

• Liver tissue engineering in the evaluation of drug safety. 29 Sep 2009
• Considerations for reducing the euthanasia procedure in toxicological studies of biopharmaceuticals using non-human primates. 29 Sep 2009
• Call from China for joint nanotech toxicity-testing effort. 29 Sep 2009
• Contact dermatitis caused by sunless tanning treatment with dihydroxyacetone in hairless descendants of Mexican hairless dogs. 29 Sep 2009
• Bioassays for evaluating the water-extractable genotoxic and toxic potential of soils polluted by metal smelters. 29 Sep 2009
• Influence of litter size on the postnatal growth of rat pups: is there a rationale for litter-size standardization in toxicity studies? 14 Sep 2009
• Fullerene exposures with oysters: embryonic, adult, and cellular responses. 13 Sep 2009
• The impact of an additional ecotoxicity test on ecological quality standards. 9 Sep 2009
• Toxicity testing gets a makeover. 8 Sep 2009
• Search for a plant for phytoremediation--what can we learn from field and hydroponic studies? 3 Sep 2009
• Phytoremediation of fungicides by aquatic macrophytes: toxicity and removal rate. Sep 2009
• Twenty-first century approaches to toxicity testing, biomonitoring, and risk assessment: perspectives from the global chemical industry. 30 Aug 2009
• Bringing exposure science into the 21st century. 30 Aug 2009
• Biodegradation of hazardous triphenylmethane dye methyl violet by Rhizobium radiobacter (MTCC 8161). 30 Aug 2009
• Differential cytotoxic effects of mono-(2-ethylhexyl) phthalate on blastomere-derived embryonic stem cells and differentiating neurons. 27 Aug 2009
• Chemical regulators have overreached. 25 Aug 2009
• Chemical-safety costs uncertain. 25 Aug 2009
• Comparison of the ocular tolerability of a latanoprost cationic emulsion versus conventional formulations of prostaglandins: an in vivo toxicity assay. 23 Aug 2009
• Tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumors. 15 Aug 2009
• Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. 13 Aug 2009

See a longer list of these articles.

Technical information about 'Toxicity Tests'

Definition: An array of tests used to determine the toxicity of a substance to living systems. These include tests on clinical drugs, foods, and environmental pollutants.

Descriptor UI: D018675

Alternative terms: Toxicity Tests; Tests, Toxicity; Test, Toxicity; Toxicity Test;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.940;

History Note: 95

Technical Notes: GEN or unspecified; prefer specifics; used for tests of drugs, food, environ pollutants, etc.; when the test itself is emphasized; coord IM with substance /tox (IM); toxic eff of a specific substance = specific substance /tox; DF: TOX TESTS