Transcription Factors - Metabolism
Research News and Information

Sunday, November 22, 2009

Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2.

29 Nov 2009 The nuclear protein methyl-transferase Retinoblastoma-interacting zinc-finger protein 1 (RIZ1) is considered to be a downstream effector of estrogen action in target tissues. Silencing of RIZ1 expression is common in many tumors. We analyzed RIZ1 ... Read more...

Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain.

8 Nov 2009 NKX3.1 is a prostate tumor suppressor belonging to the NK-2 family of homeodomain (HD) transcription factors. NK-2 family members often possess a stretch of 10-15 residues enriched in acidic amino acids, the acidic domain (AD), in the flexible, ... Read more...

Carcinoma of the breast with medullary-like features: diagnostic challenges and relationship with BRCA1 and EZH2 functions.

30 Oct 2009 This case presentation reviews the histologic distinction between pure medullary carcinoma and breast carcinomas with medullary-like features. This particular case prompts us to analyze the relationship among medullary carcinoma, basal-like breast ... Read more...

Latest indexed articles for 'Transcription Factors - Metabolism'

These are the very latest articles for this heading:

• Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. 29 Nov 2009
• Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain. 8 Nov 2009
• How do transcription factors select specific binding sites in the genome? 30 Oct 2009
• Carcinoma of the breast with medullary-like features: diagnostic challenges and relationship with BRCA1 and EZH2 functions. 30 Oct 2009
• New insights into the differentiation and function of T follicular helper cells. 30 Oct 2009
• Structural basis of typhoid: Salmonella typhi type IVb pilin (PilS) and cystic fibrosis transmembrane conductance regulator interaction. 30 Oct 2009
• Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis. 30 Oct 2009
• Polycomb group proteins: navigators of lineage pathways led astray in cancer. 30 Oct 2009
• Temperature entrainment of Drosophila's circadian clock involves the gene nocte and signaling from peripheral sensory tissues to the brain. 27 Oct 2009
• The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction. 21 Oct 2009
• Molybdenum trafficking for nitrogen fixation. 18 Oct 2009
• Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production. 16 Oct 2009
• Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. 14 Oct 2009
• Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. 13 Oct 2009
• Developmental trajectories in early hematopoiesis. 13 Oct 2009
• Impact of nonnatural amino acid mutagenesis on the in vivo function and binding modes of a transcriptional activator. 12 Oct 2009
• Modulation of vitamin d receptor activity by the corepressor hairless: differential effects of hairless isoforms. 7 Oct 2009
• Neuroscience. Nuclear power for axonal growth. 7 Oct 2009
• A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. 6 Oct 2009
• Gal4 turnover and transcription activation. 6 Oct 2009

See a longer list of these articles.

Technical information about 'Transcription Factors'

Definition: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.

Registry Number: 0

Descriptor UI: D014157

Alternative terms: Transcription Factors; Factors, Transcription; Transcription Factor; Factor, Transcription;

Related Mesh Headings: Trans-Activators;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.930;

History Note: 77

Technical Notes: in genetic transcription; /biosyn /physiol permitted; regulatory proteins go here or under REPRESSOR PROTEINS or VIRAL REGULATORY PROTEINS