Transfection
Research News and Information

Saturday, November 21, 2009

Osteoblast differentiation is functionally associated with decreased AMP kinase activity.

29 Nov 2009 Osteoblasts, originating from mesenchymal stem cells, play a pivotal role in bone formation and mineralization. Several transcription factors including runt-related transcription factor 2 (Runx2) have been reported to be essential for osteoblast ... Read more...

Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval.

29 Nov 2009 ClC-2 chloride channel is present in the brain and some transporting epithelia where its function is poorly understood. We have now demonstrated that the surface channels are rapidly internalised and approximately the 70% of the surface membrane ... Read more...

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

Latest indexed articles for 'Transfection'

These are the very latest articles for this heading:

• Osteoblast differentiation is functionally associated with decreased AMP kinase activity. 29 Nov 2009
• Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval. 29 Nov 2009
• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• Requirement of a dynein light chain in TGFbeta/Smad3 signaling. 29 Nov 2009
• PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. 29 Nov 2009
• p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. 29 Nov 2009
• Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive and -resistant prostate cancer cells. 29 Nov 2009
• A comparative study of transfection methods for RNA interference in bone marrow-derived murine dendritic cells. 30 Oct 2009
• The small heat shock protein Hsp27 protects cortical neurons against the toxic effects of beta-amyloid peptide. 30 Oct 2009
• Extracellular matrix produced by bone marrow stromal cells and by their derivative, SB623 cells, supports neural cell growth. 30 Oct 2009
• Overexpression of Bcl-XL in human neural stem cells promotes graft survival and functional recovery following transplantation in spinal cord injury. 30 Oct 2009
• Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence. 30 Oct 2009
• Dendritic cell transfected with secondary lymphoid-tissue chemokine and/or interleukin-2 gene-enhanced cytotoxicity of T-lymphocyte in human bladder tumor cell S in vitro. 30 Oct 2009
• Upregulated p27kip1 can downregulate survivin expression and inhibit telomerase activity in gastric carcinoma cells. 30 Oct 2009
• The impacts of ERCC1 gene exon VIII alternative splicing on cisplatin-resistance in ovarian cancer cells. 30 Oct 2009
• Mineralized tissue formation by BMP2-transfected pulp stem cells. 30 Oct 2009
• Periodontal gene transfer by ultrasound and nano/microbubbles. 30 Oct 2009
• Epigenetic regulation of Myc on retinoic acid receptor beta and PDLIM4 in RWPE1 cells. 30 Oct 2009
• Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells. 30 Oct 2009
• Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. 27 Oct 2009

See a longer list of these articles.

Technical information about 'Transfection'

Definition: The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.

Descriptor UI: D014162

Alternative terms: Transfection; Transfections;

Related Mesh Headings: Transformation, Bacterial; Transformation, Genetic; Electroporation;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.393.350.810; G05.355.760.860;

History Note: 78(75); was see under TRANSFORMATION, GENETIC 1975-77

Technical Notes: coordinate with recipient/genet if permitted + specific donor/genet; do not confuse with genetic transvection, an epigenetic phenomenon (index under EPIGENESIS, GENETIC)