Transforming Growth Factor beta - Administration & dosage
Research News and Information

Sunday, November 22, 2009

Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation.

30 Aug 2009 PURPOSE: The purpose of this prospective study was to evaluate the safety and effectiveness of recombinant human morphogenetic protein-2 (rhBMP-2) on an absorbable collagen sponge (ACS) compared with an autogenous bone graft when used for 2-stage ... Read more...

Novel drug delivery strategies in neuro-oncology.

29 Jun 2009 Treatment of malignant gliomas represents one of the most formidable challenges in oncology. Despite treatment with surgery, radiation therapy, and chemotherapy, the prognosis remains poor, particularly for glioblastoma, which has a median survival ... Read more...

Recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge with an osteoconductive bulking agent in posterolateral arthrodesis with instrumentation. A prospective randomized trial.

29 Jun 2009 BACKGROUND: Recombinant human bone morphogenetic protein-2 (rhBMP-2) on an absorbable collagen sponge has been shown to be a safe and effective replacement for iliac crest bone graft when used with a threaded fusion device in anterior lumbar ... Read more...

Latest indexed articles for 'Transforming Growth Factor beta - Administration & dosage'

These are the very latest articles for this heading:

• Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation. 30 Aug 2009
• Novel drug delivery strategies in neuro-oncology. 29 Jun 2009
• Recombinant human bone morphogenetic protein-2 on an absorbable collagen sponge with an osteoconductive bulking agent in posterolateral arthrodesis with instrumentation. A prospective randomized trial. 29 Jun 2009
• End plates resorptions after the applications of rhBMP-2 for interbody spinal fusions. 30 May 2009
• The effect of platelet-rich plasma and bone marrow on murine posterolateral lumbar spine arthrodesis with bone morphogenetic protein. 29 Apr 2009
• Six-year outcomes of anterior lumbar interbody arthrodesis with use of interbody fusion cages and recombinant human bone morphogenetic protein-2. 29 Apr 2009
• rhBMP-2 enhances the bone healing response in a diabetic rat segmental defect model. 30 Mar 2009
• [Beyond TGF-beta: wound healing modulation in filtering glaucoma surgery] 25 Jan 2009
• RhBMP-2 versus iliac crest bone graft for lumbar spine fusion: a randomized, controlled trial in patients over sixty years of age. 13 Dec 2008
• ISSLS prize winner: positron emission tomography and magnetic resonance imaging for monitoring interbody fusion with equine bone protein extract, recombinant human bone morphogenetic protein-2, and autograft. 29 Nov 2008
• Complications in the use of rhBMP-2 in PEEK cages for interbody spinal fusions. 29 Nov 2008
• Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations. 30 Oct 2008
• Posterior lumbar interbody fusion using rhBMP-2. 5 Oct 2008
• Occipitocervical fusion using recombinant human bone morphogenetic protein-2: adverse effects due to tissue swelling and seroma. 29 Sep 2008
• In vivo local administration of osteogenic protein-1 increases structural properties of the overstretched anterior cruciate ligament with partial midsubstance laceration: a biomechanical study in rabbits. 29 Sep 2008
• Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration. 30 Aug 2008
• Manipulating the anabolic and catabolic response in bone graft remodeling: synergism by a combination of local BMP-7 and a single systemic dosis of zoledronate. 30 Aug 2008
• Hyaluronan based porous nano-particles enriched with growth factors for the treatment of ulcers: a placebo-controlled study. 28 Aug 2008
• Use of recombinant human bone morphogenetic protein-2 to enhance posterior cervical spine fusion at 2 years of age: technical note. 13 Aug 2008
• The adjunctive effect of a binding peptide on bone morphogenetic protein enhanced bone healing in a rodent model of spinal fusion. 13 Jul 2008

See a longer list of these articles.

Technical information about 'Transforming Growth Factor beta'

Definition: A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.

Registry Number: 0

Descriptor UI: D016212

Alternative terms: Transforming Growth Factor beta; Milk Growth Factor; Factor, Milk Growth; Growth Factor, Milk; TGF-beta; TGFbeta; Platelet Transforming Growth Factor; Bone-Derived Transforming Growth Factor; Bone Derived Transforming Growth Factor;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.276.374.687; D12.644.276.954.800.720; D12.644.276.963.720; D12.776.467.374.687; D12.776.467.942.800.720; D12.776.467.960.720; D23.529.374.687; D23.529.942.800.720; D23.529.960.720;

Online Note: use TRANSFORMING GROWTH FACTORS to search TRANSFORMING GROWTH FACTOR BETA & TGF-BETA 1989-90

History Note: 91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90