Transient Receptor Potential Channels - Analysis
Research News and Information

Friday, March 12, 2010

Odontoblast TRP channels and thermo/mechanical transmission.

30 Oct 2009 Odontoblasts function as mechanosensory receptors because of the expression of mechanosensitive channels in these cells. However, it is unclear if odontoblasts direct the signal transmission evoked by heat/cold or osmotic changes. This study ... Read more...

Expression of transient receptor potential (TRP) channels in human and murine osteoblast-like cells.

25 Dec 2008 The preservation of bone mass relies on adequate proliferation, differentiation, secretion of matrix proteins and rate of apoptosis of the bone-forming osteoblasts. Although growing body of evidence indicates that the transient receptor potential ... Read more...

Role of intracellular stores in the regulation of rhythmical [Ca2+]i changes in interstitial cells of Cajal from rabbit portal vein.

21 Jun 2006 Interstitial cells of Cajal (ICCs) freshly isolated from rabbit portal vein and loaded with the Ca(2+)-sensitive indicator fluo-3 revealed rhythmical [Ca(2+)](i) changes occurring at 0.02-0.1 Hz. Each increase in [Ca(2+)](i) originated from a ... Read more...

Latest indexed articles for 'Transient Receptor Potential Channels - Analysis'

These are the very latest articles for this heading:

• Odontoblast TRP channels and thermo/mechanical transmission. 30 Oct 2009
• Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin. 10 Mar 2009
• Expression of transient receptor potential (TRP) channels in human and murine osteoblast-like cells. 25 Dec 2008
• Role of intracellular stores in the regulation of rhythmical [Ca2+]i changes in interstitial cells of Cajal from rabbit portal vein. 21 Jun 2006
• Recent developments in vascular endothelial cell transient receptor potential channels. 26 Oct 2005
• Transient receptor potential channels in the inner ear: presence of transient receptor potential channel subfamily 1 and 4 in the guinea pig inner ear. 30 Aug 2005

See a longer list of these articles.

Technical information about 'Transient Receptor Potential Channels'

Definition: A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN repeats are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.

Registry Number: 0

Descriptor UI: D050051

Alternative terms: Transient Receptor Potential Channels; TRP Membrane Proteins; Membrane Proteins, TRP; Proteins, TRP Membrane; TRP Cation Channels; Cation Channels, TRP; Channels, TRP Cation;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.157.530.400.901; D12.776.543.585.400.901;

History Note: 2006

Technical Notes: note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN