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Triiodothyronine
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Definition of 'Triiodothyronine'

A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.

Common names: Triiodothyronine; T3 Thyroid Hormone; Thyroid Hormone, T3; Liothyronine; Cytomel

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Sunday, November 22, 2009

Type 1 deiodinase activity and generation of triiodothyronine (T3) in prostate of sexually active rats.

30 Oct 2009 BACKGROUND: Thyroxine (T(4)) and triiodothyronine (T(3)) are involved in the development and function of the male reproductive system. The type 1 deiodinase enzyme (D1) plays a major role in the intracellular conversion of T(4) to the active form, ... Read more...


The influence of thyroid hormones on periodontitis-related bone loss and tooth-supporting alveolar bone: a histological study in rats.

20 Oct 2009 BACKGROUND AND OBJECTIVE: Recent studies have pointed to potentially periodontal risk indicators, however no information is available on the impact of changes in thyroid hormone levels on the progression of periodontitis and on the quality of ... Read more...


Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells.

7 Oct 2009 The type 3 iodothyronine deiodinase (D3) is the primary deiodinase that inactivates thyroid hormone. Immunoprecipitation of D3, followed by fluorescent two-dimensional difference gel electrophoresis and mass spectrometry, identified peroxiredoxin 3 ... Read more...

 

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Technical information about 'Triiodothyronine'

Definition: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.

Chemical name: L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-

Registry Number: 6893-02-3

Descriptor UI: D014284

Alternative terms: Triiodothyronine; T3 Thyroid Hormone; Thyroid Hormone, T3; Liothyronine; Cytomel;

Related Mesh Headings: Receptors, Thyroid Hormone;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D06.472.931.740.385; D12.125.072.050.767.741.894;

Online Note: use TRIIODOTHYRONINE to search LIOTHYRONINE 1966

History Note: LIOTHYRONINE was heading 1963-66

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