Trimethoprim-Sulfamethoxazole Combination - Therapeutic use
Research News and Information

Sunday, November 22, 2009

Antibiotic prophylaxis and recurrent urinary tract infection in children.

27 Oct 2009 BACKGROUND: Antibiotics are widely administered to children with the intention of preventing urinary tract infection, but adequately powered, placebo-controlled trials regarding efficacy are lacking. This study from four Australian centers examined ... Read more...

Risk factors, clinical features, and outcomes of listeriosis in solid-organ transplant recipients: a matched case-control study.

13 Oct 2009 BACKGROUND: Solid-organ transplant (SOT) recipients are classically considered to be at increased risk for listeriosis. However, risk factors for this infection have not been assessed. METHODS: We carried out a multicenter, matched case-control ... Read more...

Outcome from treatment of Pneumocystis jirovecii pneumonia with co-trimoxazole.

30 Aug 2009 A retrospective case-notes audit of 359 HIV-1-infected adult patients with first-episode laboratory-confirmed Pneumocystis jirovecii pneumonia treated with co-trimoxazole (from 1987 adjuvant steroids were used if PaO(2) <9.3 kPa) showed that only ... Read more...

Latest indexed articles for 'Trimethoprim-Sulfamethoxazole Combination - Therapeutic use'

These are the very latest articles for this heading:

• Antimicrobial prophylaxis for urinary tract infection in children. 27 Oct 2009
• Antibiotic prophylaxis and recurrent urinary tract infection in children. 27 Oct 2009
• Risk factors, clinical features, and outcomes of listeriosis in solid-organ transplant recipients: a matched case-control study. 13 Oct 2009
• Clinical and tomographic features of macular punctate outer retinal toxoplasmosis. 29 Sep 2009
• Outcome from treatment of Pneumocystis jirovecii pneumonia with co-trimoxazole. 30 Aug 2009
• Stevens-Johnson syndrome and toxic epidermal necrolysis: consequence of treatment of an emerging pathogen. 30 Jul 2009
• Empyema thoracis due to nocardiosis and Mycobacterium tuberculosis mixed infections in an AIDS patient. 29 Jun 2009
• Confluent molluscum contagiosum covering the eyelids of an HIV-positive child. 29 Jun 2009
• The role of primary care prescribers in the diagnosis and management of community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections. 29 Jun 2009
• Pulmonary nocardiosis from a tertiary care hospital in Southern India. 29 Jun 2009
• Transconjunctival orbital invasion by methicillin-resistant Staphylococcus aureus. 29 Jun 2009
• Nocardiosis at the turn of the century. 29 Jun 2009
• Evolving health effects of Pneumocystis: one hundred years of progress in diagnosis and treatment. 22 Jun 2009
• Linking HIV-infected TB patients to cotrimoxazole prophylaxis and antiretroviral treatment in India. 20 Jun 2009
• Therapeutic failure in a renal transplant patient with Pneumocystis jiroveci pneumonia: a case report. 30 May 2009
• Pediatric infestations. 30 May 2009
• High early mortality in patients with chronic acquired immunodeficiency syndrome diarrhea initiating antiretroviral therapy in Haiti: a case-control study. 30 May 2009
• Empiric antimicrobial therapy for pediatric skin and soft-tissue infections in the era of methicillin-resistant Staphylococcus aureus. 24 May 2009
• Isospora cholangiopathy: case study with histologic characterization and molecular confirmation. 15 May 2009
• Staphylococcus aureus bloodstream infections: definitions and treatment. 13 May 2009

See a longer list of these articles.

Technical information about 'Trimethoprim-Sulfamethoxazole Combination'

Definition: This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

Chemical name: Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine

Registry Number: 8064-90-2

Descriptor UI: D015662

Alternative terms: Trimethoprim-Sulfamethoxazole Combination; Trimethoprim Sulfamethoxazole Combination; Centran; Centrin; Co-Trimoxazole; Co Trimoxazole; Cotrimoxazole; Trimethoprim-Sulfamethoxazole; Trimethoprim Sulfamethoxazole; Insozalin; Sulfamethoxazole-Trimethoprim Combination; Sulfamethoxazole Trimethoprim Combination; TMP SMX; TMP-SMX; Trimedin; Trimezole; Eslectin; Bactifor; Bactrim; Biseptol; Biseptol-480; Biseptol 480; Biseptol480; Drylin; Eusaprim; Kepinol; Kepinol Forte; Lescot; Metomide; Oriprim; Septra; Septrin; Sulprim; Sumetrolim; Trimethoprimsulfa; Trimosulfa; Abactrim;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Infective Agents, Urinary; Antimalarials; Anti-Infective Agents;

Tree Number: D02.065.884.725.867.500; D02.092.146.807.867.500; D02.886.590.700.725.867.500; D03.383.742.906.500;

History Note: 90

Technical Notes: DF: TMP SMX