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Trimethoprim-Sulfamethoxazole Combination
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Definition of 'Trimethoprim-Sulfamethoxazole Combination'

This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

Common names: Trimethoprim-Sulfamethoxazole Combination; Trimethoprim Sulfamethoxazole Combination; Centran; Centrin; Co-Trimoxazole; Co Trimoxazole; Cotrimoxazole; Trimethoprim-Sulfamethoxazole; Trimethoprim Sulfamethoxazole; Insozalin; Sulfamethoxazole-Trimethoprim Combination

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Monday, November 23, 2009

Antibiotic prophylaxis and recurrent urinary tract infection in children.

27 Oct 2009 BACKGROUND: Antibiotics are widely administered to children with the intention of preventing urinary tract infection, but adequately powered, placebo-controlled trials regarding efficacy are lacking. This study from four Australian centers examined ... Read more...


Risk factors, clinical features, and outcomes of listeriosis in solid-organ transplant recipients: a matched case-control study.

13 Oct 2009 BACKGROUND: Solid-organ transplant (SOT) recipients are classically considered to be at increased risk for listeriosis. However, risk factors for this infection have not been assessed. METHODS: We carried out a multicenter, matched case-control ... Read more...


Outcome from treatment of Pneumocystis jirovecii pneumonia with co-trimoxazole.

30 Aug 2009 A retrospective case-notes audit of 359 HIV-1-infected adult patients with first-episode laboratory-confirmed Pneumocystis jirovecii pneumonia treated with co-trimoxazole (from 1987 adjuvant steroids were used if PaO(2) <9.3 kPa) showed that only ... Read more...

 

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Technical information about 'Trimethoprim-Sulfamethoxazole Combination'

Definition: This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

Chemical name: Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine

Registry Number: 8064-90-2

Descriptor UI: D015662

Alternative terms: Trimethoprim-Sulfamethoxazole Combination; Trimethoprim Sulfamethoxazole Combination; Centran; Centrin; Co-Trimoxazole; Co Trimoxazole; Cotrimoxazole; Trimethoprim-Sulfamethoxazole; Trimethoprim Sulfamethoxazole; Insozalin; Sulfamethoxazole-Trimethoprim Combination; Sulfamethoxazole Trimethoprim Combination; TMP SMX; TMP-SMX; Trimedin; Trimezole; Eslectin; Bactifor; Bactrim; Biseptol; Biseptol-480; Biseptol 480; Biseptol480; Drylin; Eusaprim; Kepinol; Kepinol Forte; Lescot; Metomide; Oriprim; Septra; Septrin; Sulprim; Sumetrolim; Trimethoprimsulfa; Trimosulfa; Abactrim;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Infective Agents, Urinary; Antimalarials; Anti-Infective Agents;

Tree Number: D02.065.884.725.867.500; D02.092.146.807.867.500; D02.886.590.700.725.867.500; D03.383.742.906.500;

History Note: 90

Technical Notes: DF: TMP SMX

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