Trimipramine - Pharmacology
Research News and Information

Sunday, November 22, 2009

The effect of trimipramine on dream recall and dream emotions in depressive outpatients.

26 Apr 2009 Trimipramine is a sedating tricyclic antidepressant which is not only effective in the treatment of depression but also in primary insomnia. In contrast to most other antidepressants, trimipramine does not affect rapid eye movement sleep. In a large ... Read more...

Receptor occupancy of mirtazapine determined by PET in healthy volunteers.

23 Jul 2007 RATIONALE: Molecular tools are needed for assessing anti-depressant actions by positron emission tomography (PET) in the living human brain. OBJECTIVES: This study determined whether [(11)C]mirtazapine is an appropriate molecular tool for use with ... Read more...

Shifts in metabolic parameters surrounding glucose homoeostasis resulting from tricyclic antidepressant therapy: implications of insulin resistance?

30 Dec 2006 This study displayed the physiological effects the tricyclic antidepressants amitriptyline or trimipramine have on glucose homoeostasis in male Wistar rats. An insulin secreting cell line (INS-1) was also used to determine effects tricyclic ... Read more...

Latest indexed articles for 'Trimipramine - Pharmacology'

These are the very latest articles for this heading:

• The effect of trimipramine on dream recall and dream emotions in depressive outpatients. 26 Apr 2009
• Receptor occupancy of mirtazapine determined by PET in healthy volunteers. 23 Jul 2007
• Shifts in metabolic parameters surrounding glucose homoeostasis resulting from tricyclic antidepressant therapy: implications of insulin resistance? 30 Dec 2006
• The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine. 17 May 2006
• Trimipramine in primary insomnia: results of a polysomnographic double-blind controlled study. 30 Aug 2002
• Effects of the atypical antidepressant trimipramine on neuronal excitability and long-term potentiation in guinea pig hippocampal slices. 30 Jan 2002
• Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study. 30 Dec 2000
• Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump. 30 Mar 2000
• Trimipramine fails to exert antimanic efficacy: a case of the discrepancy between in vitro rationale and clinical efficacy. 30 Aug 1999
• Effects of the atypical antidepressant trimipramine on field potentials in the low Mg2+-model in guinea pig hippocampal slices. 30 Jul 1998
• Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics. 27 Feb 1998
• Repeated trimipramine induces dopamine D2/D3 and alpha1-adrenergic up-regulation. 30 Dec 1997
• Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response. 29 Apr 1997
• Male reproductive systems under chronic fluoxetine or trimipramine treatment. 28 Feb 1996
• Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance. 4 Apr 1995
• Effect of long-term administration of antidepressant drugs on the 5-HT3 receptors that enhance the electrically evoked release of [3H]noradrenaline in the rat hippocampus. 10 Dec 1994
• Modulation of the AMPA receptor by phospholipase A2: effect of the antidepressant trimipramine. 30 Jan 1994
• A comparison of the cardiac safety and therapeutic efficacy of trimipramine versus doxepin in geriatric depressed patients. 30 Jul 1993
• [3H]paroxetine binding and serotonin content of rat brain: absence of changes following antidepressant treatments. 20 Apr 1993
• Chronic effects of trimipramine, an antidepressant, on hippocampal synaptic plasticity. 27 Feb 1993

See a longer list of these articles.

Technical information about 'Trimipramine'

Definition: Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.

Chemical name: 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-

Registry Number: 739-71-9

Descriptor UI: D014299

Alternative terms: Trimipramine; Trimeprimine; 10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine; Eldoral; AWD.pharma Brand of Trimipramine Maleate; Herphonal; Temmler Brand of Trimipramine Maleate; Hexal Brand of Trimipramine; Trimipramine Hexal Brand; Trimineurin; Novo-Tripramine; Novo Tripramine; NovoTripramine; Novopharm Brand of Trimipramine Maleate; Nu-Trimipramine; Nu Trimipramine; NuTrimipramine; Nu-Pharm Brand of Trimipramine Maleate; Nu Pharm Brand of Trimipramine Maleate; Rhotrimine; Rhodiapharm Brand of Trimipramine Maleate; Stangyl; Aventis Brand of Trimipramine Maleate; Surmontil; Aventis Brand of Trimipramine; Trimipramine Aventis Brand; Surmontil Maleate; Rhone-Poulenc Rorer Brand of Trimipramine Maleate; Rhone Poulenc Rorer Brand of Trimipramine Maleate; Odyssey Brand of Trimipramine Maleate; Trimidura; Merck dura Brand of Trimipramine Maleate; Trimineurin Maleate; Neuro Hexal Brand of Trimipramine Maleate; Trimipramin AZU; Azupharma Brand of Trimipramine Maleate; Trimipramin beta; betapharm Brand of Trimipramine Maleate; Trimipramin Stada; Stadapharm Brand of Trimipramine Maleate; Trimipramin-neurazpharm; Trimipramin neurazpharm; Trimipraminneurazpharm; neurazpharm Brand of Trimipramine Maleate; Trimipramine Maleate; Trimipramine Maleate (1:1); Trimipramine Maleate (1:1), (+)-Isomer; Trimipramine Maleate (1:1), (+-)-Isomer; Trimipramine Maleate (1:1), (-)-Isomer; Trimipramine Mesylate; Trimipramine Monohydrochloride; Trimipramine, (+-)-Isomer; Trimipramine, (-)-Isomer; Apo-Trimip; Apo Trimip; ApoTrimip; Apotex Brand of Trimipramine Maleate;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic;

Tree Number: D03.494.240.918;

Online Note: search DIBENZAZEPINES 1968-74

History Note: 91(75); was see under DIBENZAZEPINES 1975-90