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Troponin T - Metabolism
Research News and Information
Definition of 'Troponin T'One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY. Common names: Troponin T; T, Troponin; Troponin-T; Troponin T2; T2, Troponin; Troponin T1; T1, Troponin |
Monday, November 23, 2009
29 Nov 2009
In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or ... Read more...
22 Aug 2009
BACKGROUND: The significance and clinical role of cardiac troponin testing after coronary artery bypass grafting remain unclear. METHODS AND RESULTS: Cardiac troponin T (cTnT) was measured during the first 24 hours after coronary artery bypass graft ... Read more...
Impact of cardiac troponin T N-terminal deletion and phosphorylation on myofilament function.
16 Aug 2009
Cardiac troponin T (cTnT) is a phosphoprotein that modulates cardiac muscle contraction through its extensive and diverse interactions with neighboring thin filament proteins. Its N-terminal half is the "glue" that anchors the troponin complex to ... Read more...
Latest indexed articles for 'Troponin T - Metabolism'
These are the very latest articles for this heading:
- OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells.
29 Nov 2009 - Prospective, comprehensive assessment of cardiac troponin T testing after coronary artery bypass graft surgery.
22 Aug 2009 - Impact of cardiac troponin T N-terminal deletion and phosphorylation on myofilament function.
16 Aug 2009 - Back to the future: new techniques show that forgotten phosphorylation sites are present in contractile proteins of the heart whilst intensively studied sites appear to be absent.
23 Jul 2009 - Impairment of diastolic function by lack of frequency-dependent myofilament desensitization rabbit right ventricular hypertrophy.
19 Jul 2009 - Functional analysis of a unique troponin c mutation, GLY159ASP, that causes familial dilated cardiomyopathy, studied in explanted heart muscle.
4 Jul 2009 - Acute pulmonary embolism registry in the Malopolska region - clinical course.
29 Jun 2009 - Beating behavior of primary neonatal cardiomyocytes and cardiac-differentiated P19.CL6 cells on different extracellular matrix components.
16 Jun 2009 - Reduced force production during low blood flow to the heart correlates with altered troponin I phosphorylation.
7 Jun 2009 - Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models.
3 Jun 2009 - CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA.
12 May 2009 - Raf-1: a novel cardiac troponin T kinase.
19 Apr 2009 - Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart.
15 Apr 2009 - Post-exercise release of cardiac troponins.
12 Apr 2009 - Troponin T elevation after implanted defibrillator discharge predicts survival.
11 Apr 2009 - Intracardiac injection of erythropoietin induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model.
30 Mar 2009 - Structural basis for the activation of muscle contraction by troponin and tropomyosin.
29 Mar 2009 - Comparative transcriptional and biochemical studies in muscle of myotonic dystrophies (DM1 and DM2).
25 Mar 2009 - Sivelestat reduces myocardial ischemia and reperfusion injury in rat hearts even when administered after onset of myocardial ischemia.
9 Mar 2009 - Functional aberration of myofibrils by cardiomyopathy-causing mutations in the coiled-coil region of the troponin-core domain.
7 Mar 2009
See a longer list of these articles.
Technical information about 'Troponin T'
Definition: One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Registry Number: 0
Descriptor UI: D020107
Alternative terms: Troponin T; T, Troponin; Troponin-T; Troponin T2; T2, Troponin; Troponin T1; T1, Troponin;
Related Mesh Headings: Cardiomyopathy, Hypertrophic, Familial;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D05.750.078.730.825.962; D12.776.210.500.910.962; D12.776.220.525.825.962;
History Note: 99; use TROPONIN T (NM) 1981-98
Technical Notes: TROPONIN C & TROPONIN I are also available