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Troponin T - Metabolism
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Definition of 'Troponin T'

One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

Common names: Troponin T; T, Troponin; Troponin-T; Troponin T2; T2, Troponin; Troponin T1; T1, Troponin

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Monday, November 23, 2009

OPLA scaffold, collagen I, and horse serum induce an higher degree of myogenic differentiation of adult rat cardiac stem cells.

29 Nov 2009 In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or ... Read more...


Prospective, comprehensive assessment of cardiac troponin T testing after coronary artery bypass graft surgery.

22 Aug 2009 BACKGROUND: The significance and clinical role of cardiac troponin testing after coronary artery bypass grafting remain unclear. METHODS AND RESULTS: Cardiac troponin T (cTnT) was measured during the first 24 hours after coronary artery bypass graft ... Read more...


Impact of cardiac troponin T N-terminal deletion and phosphorylation on myofilament function.

16 Aug 2009 Cardiac troponin T (cTnT) is a phosphoprotein that modulates cardiac muscle contraction through its extensive and diverse interactions with neighboring thin filament proteins. Its N-terminal half is the "glue" that anchors the troponin complex to ... Read more...

 

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Technical information about 'Troponin T'

Definition: One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

Registry Number: 0

Descriptor UI: D020107

Alternative terms: Troponin T; T, Troponin; Troponin-T; Troponin T2; T2, Troponin; Troponin T1; T1, Troponin;

Related Mesh Headings: Cardiomyopathy, Hypertrophic, Familial;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.730.825.962; D12.776.210.500.910.962; D12.776.220.525.825.962;

History Note: 99; use TROPONIN T (NM) 1981-98

Technical Notes: TROPONIN C & TROPONIN I are also available

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