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Tryptophan
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Definition of 'Tryptophan'

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Common names: Tryptophan; L-Tryptophan; L Tryptophan; Levotryptophan; Ardeydorm; Ardeytropin; Ardeypharm Brand of Tryptophan; Kalma Brand of Tryptophan; Niddapharm Brand of Tryptophan; L-Tryptophan-ratiopharm; L Tryptophan ratiopharm; Ratiopharm Brand of Tryptophan; ratio-Tryptophan; ratio Tryptophan

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Saturday, March 20, 2010

The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp.

21 Dec 2009 BACKGROUND: The JAL antigen (Rh48) was discovered more than 30 years ago when it caused hemolytic disease of the fetus and newborn in an African American family. A decade later it was found to cause hemolytic disease of the fetus and newborn in a ... Read more...


Role of tryptophan-tryptophan interactions in Trpzip beta-hairpin formation, structure, and stability.

Nov 2009 A series of beta-hairpin peptides based on variations of the TrpZip2 sequence, SWTWENGKWTWK, of Cochran and co-workers were studied using electronic circular dichroism (CD) and infrared (IR) spectra by varying temperature and pH. Selected tryptophan ... Read more...


Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy.

18 Oct 2009 In sickle cell hemoglobin, individual tetramers associate into long fibers as a consequence of the mutation at the beta6 position. In this study UV resonance Raman spectroscopy is used to monitor the formation of Hb S fibers in real time through ... Read more...

 

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Technical information about 'Tryptophan'

Definition: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Chemical name: Tryptophan

Registry Number: 73-22-3

Descriptor UI: D014364

Alternative terms: Tryptophan; L-Tryptophan; L Tryptophan; Levotryptophan; Ardeydorm; Ardeytropin; Ardeypharm Brand of Tryptophan; Kalma Brand of Tryptophan; Niddapharm Brand of Tryptophan; L-Tryptophan-ratiopharm; L Tryptophan ratiopharm; Ratiopharm Brand of Tryptophan; ratio-Tryptophan; ratio Tryptophan; Tryptophan Metabolism Alterations; PMS-Tryptophan; PMS Tryptophan; Pharmascience Brand of Tryptophan; Trofan; Upsher-Smith Brand of Tryptophan; Tryptacin; ICN Brand of Tryptophan; Tryptan; Optimax; Merck Brand of Tryptophan; Lyphan; Naturruhe; esparma Brand of Tryptophan;

Related Mesh Headings: Eosinophilia-Myalgia Syndrome;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Antidepressive Agents, Second-Generation;

Tree Number: D12.125.072.050.850; D12.125.142.875;

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