Twist Transcription Factor - Genetics
Research News and Information

Saturday, November 21, 2009

WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?

30 Aug 2009 Based on characterization of both genomic and expression status of WT1 and CTNNB1 (beta-catenin) in a series of 60 Wilms tumor samples, combined with genome-wide expression profiling of these tumors, normal mature and fetal kidney controls, we show ... Read more...

Twist expression promotes migration and invasion in hepatocellular carcinoma.

16 Jul 2009 BACKGROUND: Twist, a transcription factor of the basic helix-loop-helix class, is reported to regulate cancer metastasis. It is known to induce epithelial-mesenchymal transition (EMT). In this study, we evaluated the expression of twist and its ... Read more...

Breast cancer risk is not increased in individuals with TWIST1 mutation confirmed Saethre-Chotzen syndrome: an Australian multicenter study.

29 Jun 2009 Saethre-Chotzen syndrome (SCS) is a rare autosomal dominant syndrome involving craniosynostosis, craniofacial abnormalities, and syndactyly. A recent Scandinavian study reported an increased risk of breast cancer in individuals with a clinical ... Read more...

Latest indexed articles for 'Twist Transcription Factor - Genetics'

These are the very latest articles for this heading:

• WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries? 30 Aug 2009
• Twist expression promotes migration and invasion in hepatocellular carcinoma. 16 Jul 2009
• Breast cancer risk is not increased in individuals with TWIST1 mutation confirmed Saethre-Chotzen syndrome: an Australian multicenter study. 29 Jun 2009
• Negative regulation of TIMP1 is mediated by transcription factor TWIST1. 29 Jun 2009
• Phylogenetic and evolutionary relationships and developmental expression patterns of the zebrafish twist gene family. 28 Jun 2009
• A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. 21 Jun 2009
• Characterization of sequences in human TWIST required for nuclear localization. 15 Jun 2009
• Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. 3 Jun 2009
• Integration of differentiation signals during indirect flight muscle formation by a novel enhancer of Drosophila vestigial gene. Jun 2009
• Discussion. Reoperation for intracranial hypertension in TWIST1-confirmed Saethre-Chotzen syndrome: a 15-year review. 30 May 2009
• Reoperation for intracranial hypertension in TWIST1-confirmed Saethre-Chotzen syndrome: a 15-year review. 30 May 2009
• Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. 29 May 2009
• Hypermethylated genes as biomarkers of cancer in women with pathologic nipple discharge. 24 May 2009
• Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma. 16 May 2009
• Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis. 11 May 2009
• A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis. 2 May 2009
• Expression of the transcription factor snail and its target gene twist are associated with malignancy in pheochromocytomas. 30 Apr 2009
• Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck. 19 Apr 2009
• The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. 19 Apr 2009
• Mechanical signals trigger Myosin II redistribution and mesoderm invagination in Drosophila embryos. 12 Apr 2009

See a longer list of these articles.

Technical information about 'Twist Transcription Factor'

Definition: A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essential for proper gastrulation and MESODERM formation. It plays an important role in EMBRYONIC DEVELOPMENT and CELL DIFFERENTIATION of MUSCLE CELLS, and is found in a wide variety of organisms.

Registry Number: 0

Descriptor UI: D051879

Alternative terms: Twist Transcription Factor; Transcription Factor, Twist; Twist Protein;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.103.875; D12.776.930.125.875;

History Note: 2006(1990)