Twist Transcription Factor
Research News and Information

Saturday, November 21, 2009

WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?

30 Aug 2009 Based on characterization of both genomic and expression status of WT1 and CTNNB1 (beta-catenin) in a series of 60 Wilms tumor samples, combined with genome-wide expression profiling of these tumors, normal mature and fetal kidney controls, we show ... Read more...

Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila.

3 Aug 2009 PAZ/PIWI domain (PPD) proteins carrying small RNAs (sRNAs) function in gene and genome regulation. The ciliate Tetrahymena thermophila encodes numerous PPD proteins exclusively of the Piwi clade. We show that the three Tetrahymena Piwi family ... Read more...

Bone morphogenetic protein 7 induces mesenchymal-to-epithelial transition in melanoma cells, leading to inhibition of metastasis.

28 Jul 2009 Bone morphogenetic protein (BMP) 7 counteracts physiological epithelial-to-mesenchymal transition, a process that is indicative of epithelial plasticity in developmental stages. Because epithelial-to-mesenchymal transition and its reversed process ... Read more...

Latest indexed articles for 'Twist Transcription Factor'

These are the very latest articles for this heading:

• WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries? 30 Aug 2009
• Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. 3 Aug 2009
• Bone morphogenetic protein 7 induces mesenchymal-to-epithelial transition in melanoma cells, leading to inhibition of metastasis. 28 Jul 2009
• Twist expression promotes migration and invasion in hepatocellular carcinoma. 16 Jul 2009
• Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells. 4 Jul 2009
• Breast cancer risk is not increased in individuals with TWIST1 mutation confirmed Saethre-Chotzen syndrome: an Australian multicenter study. 29 Jun 2009
• Negative regulation of TIMP1 is mediated by transcription factor TWIST1. 29 Jun 2009
• Phylogenetic and evolutionary relationships and developmental expression patterns of the zebrafish twist gene family. 28 Jun 2009
• A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. 21 Jun 2009
• Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression. 16 Jun 2009
• Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease. 15 Jun 2009
• Characterization of sequences in human TWIST required for nuclear localization. 15 Jun 2009
• Re: Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells. 7 Jun 2009
• Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. 3 Jun 2009
• Integration of differentiation signals during indirect flight muscle formation by a novel enhancer of Drosophila vestigial gene. Jun 2009
• Twist: a new link from hypoxia to fibrosis. 30 May 2009
• Discussion. Reoperation for intracranial hypertension in TWIST1-confirmed Saethre-Chotzen syndrome: a 15-year review. 30 May 2009
• Reoperation for intracranial hypertension in TWIST1-confirmed Saethre-Chotzen syndrome: a 15-year review. 30 May 2009
• Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. 29 May 2009
• Hypermethylated genes as biomarkers of cancer in women with pathologic nipple discharge. 24 May 2009

See a longer list of these articles.

Technical information about 'Twist Transcription Factor'

Definition: A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essential for proper gastrulation and MESODERM formation. It plays an important role in EMBRYONIC DEVELOPMENT and CELL DIFFERENTIATION of MUSCLE CELLS, and is found in a wide variety of organisms.

Registry Number: 0

Descriptor UI: D051879

Alternative terms: Twist Transcription Factor; Transcription Factor, Twist; Twist Protein;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.103.875; D12.776.930.125.875;

History Note: 2006(1990)