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Tyrosine - Metabolism
Research News and Information
Definition of 'Tyrosine'A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. Common names: Tyrosine; para-Tyrosine; para Tyrosine; Tyrosine, L-isomer; Tyrosine, L isomer; L-Tyrosine; L Tyrosine |
Monday, November 23, 2009
Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking.
27 Oct 2009 
Modification of NMDA receptor function and trafficking contributes to the regulation of synaptic transmission and is important for several forms of synaptic plasticity. Here, we report that NMDA receptor subunits NR2A and NR2B have two distinct ... Read more...
10 Oct 2009 Mutations in the neuronal protein alpha-synuclein cause familial Parkinson disease. Phosphorylation of alpha-synuclein at serine 129 is prominent in Parkinson disease and influences alpha-synuclein neurotoxicity. Here we report that alpha-synuclein ... Read more...
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
29 Sep 2009 DYRK1A is a dual-specificity protein kinase that autophosphorylates a conserved tyrosine residue in the activation loop but phosphorylates exogenous substrates only at serine or threonine residues. Tyrosine autophosphorylation of DYRKs is a one-off ... Read more...
Latest indexed articles for 'Tyrosine - Metabolism'
These are the very latest articles for this heading:
- Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. 27 Oct 2009
- Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. 10 Oct 2009
- Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation. 29 Sep 2009
- PYK2/PDZ-RhoGEF links Ca2+ signaling to RhoA. 29 Sep 2009
- Signal transduction responses to lysophosphatidic acid and sphingosine 1-phosphate in human prostate cancer cells. 29 Sep 2009
- Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function. 28 Sep 2009
- JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. 25 Sep 2009
- Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss. 23 Sep 2009
- Cell biology. Evolving cell signals.
23 Sep 2009 - Mutagenesis and evolution of sulfated antibodies using an expanded genetic code. 20 Sep 2009
- eNOS uncoupling and endothelial dysfunction in aged vessels. 16 Sep 2009
- Reconstitution and engineering of apoptotic protein interactions on the bacterial cell surface. 15 Sep 2009
- 19F NMR studies of alpha-synuclein conformation and fibrillation. 13 Sep 2009
- Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats. 9 Sep 2009
- Peroxynitrite induces tyrosine residue modifications in synaptophysin C-terminal domain, affecting its interaction with src. 6 Sep 2009
- SRC substrate surprise. 6 Sep 2009
- SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo. 2 Sep 2009
- Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite. 2 Sep 2009
- Membrane binding mode of intrinsically disordered cytoplasmic domains of T cell receptor signaling subunits depends on lipid composition. 2 Sep 2009
- Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection. 30 Aug 2009
See a longer list of these articles.
Technical information about 'Tyrosine'
Definition: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Chemical name: Tyrosine
Registry Number: 55520-40-6
Descriptor UI: D014443
Alternative terms: Tyrosine; para-Tyrosine; para Tyrosine; Tyrosine, L-isomer; Tyrosine, L isomer; L-Tyrosine; L Tyrosine;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D12.125.072.050.875;
Technical Notes: /blood: consider also TYROSINEMIAS